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Yuan-Ji Day

Researcher at Memorial Hospital of South Bend

Publications -  50
Citations -  1411

Yuan-Ji Day is an academic researcher from Memorial Hospital of South Bend. The author has contributed to research in topics: Inflammation & Superoxide. The author has an hindex of 18, co-authored 50 publications receiving 1145 citations. Previous affiliations of Yuan-Ji Day include Chang Gung University & Chang Gung Memorial Hospital.

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Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment.

TL;DR: The results indicate that tumor-associated myeloid cells, including macrophages, DCs, and MDSCs all express immunosuppressive A2ARs that are potential targets of adenosine receptor blockers to enhance immune killing of tumors.
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Tumor-Derived Chemokine CCL5 Enhances TGF-β–Mediated Killing of CD8+ T Cells in Colon Cancer by T-Regulatory Cells

TL;DR: It is established that CCL5/CCR5 signaling recruits T(reg) to tumors and enhances their ability to kill antitumor CD8(+) T cells, thereby defining a novel mechanism of immune escape in colorectal cancer.
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Extracellular adenosine regulates naive T cell development and peripheral maintenance.

TL;DR: Adenosine receptor signaling inhibits TCR-induced activation of PI3K–Akt to reduce IL-7Rα expression on T cells, thereby regulating development and maintenance of naive T cells in the periphery.
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Resveratrol exerts anti-obesity effects in high-fat diet obese mice and displays differential dosage effects on cytotoxicity, differentiation, and lipolysis in 3T3-L1 cells.

TL;DR: It is suggested that resveratrol possessed anti-obesity effects by induction of cytotoxicity at high dosage and that it influences preadipocyte differentiation and mature adipocyte lipolysis at low concentration.