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Yue Ge
Researcher at Soochow University (Suzhou)
Publications - 5
Citations - 283
Yue Ge is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Haematopoiesis & Myeloid leukemia. The author has an hindex of 3, co-authored 4 publications receiving 243 citations.
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Journal ArticleDOI
Anti-leukemia activity of PVP-coated silver nanoparticles via generation of reactive oxygen species and release of silver ions
Dawei Guo,Lingying Zhu,Zhihai Huang,Haixia Zhou,Yue Ge,Wenjuan Ma,Jie Wu,Xiuyan Zhang,Xuefeng Zhou,Yu Zhang,Yun Zhao,Ning Gu +11 more
TL;DR: It is found that AgNPs could inhibit the viability of AML cells including the isolates from AML patients, and supported the model that both generation of ROS and release of silver ions played critical roles in the AgnPs-induced cytotoxic effect against AMl cells.
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Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth.
Haixia Zhou,Yue Ge,Lili Sun,Wenjuan Ma,Jie Wu,Xiuyan Zhang,Xiaohui Hu,Connie J. Eaves,Depei Wu,Yun Zhao +9 more
TL;DR: GAS2 was up-regulated in CML cells including CD34+ progenitor cells compared to their normal counterparts and the inhibition of GAS2 impairs the growth of Cml cells, which indicates GAS1 is a novel regulator of C ML cells and a potential therapeutic target of this disease.
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GAS2–Calpain2 axis contributes to the growth of leukemic cells
TL;DR: The deregulation of GAS2 in both AML and ALL and the requirement of Gas2-Calpain2 axis for the growth of leukemic cells will help to understand the molecular pathogenesis of hematological malignancies and possibly to develop novel approaches to treat these deadly diseases.
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ZFX modulates the growth of human leukemic cells via B4GALT1.
Jie Wu,Lun Xiao,Haixia Zhou,Hong Liu,Yue Ge,Jing Yang,Yuanyuan Li,Depei Wu,Yun Zhao,Xiuyan Zhang +9 more
TL;DR: It is demonstrated that ZFX is aberrantly expressed in multiple human leukemic cells and it modulates the growth and drug response of leukeMIC cells partially via B4GALT1, which suggests that Z FX is a new regulator of leukedmic cells.
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[Agkistrodon halys venom antitumor component-I inhibits vasculogenic mimicry in triple-negative breast cancer cells in vitro by down-regulating MMP2].
TL;DR: AHVAC-I inhibits VM formation in triplenegative breast cancer cells in vitro by down-regulating MMP2 production by blocking the expression levels of matrix metalloproteinase-2 and MMP9 in treated cells.