Y
Yuguang Wang
Researcher at Harvard University
Publications - 25
Citations - 958
Yuguang Wang is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 7, co-authored 10 publications receiving 600 citations. Previous affiliations of Yuguang Wang include Peking University.
Papers
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Journal ArticleDOI
Antimicrobial Photodynamic Therapy to Control Clinically Relevant Biofilm Infections.
Xiaoqing Hu,Ying-Ying Huang,Yuguang Wang,Yuguang Wang,Xiaoyuan Wang,Michael R. Hamblin,Michael R. Hamblin +6 more
TL;DR: Antimicrobial Photodynamic therapy (aPDT) had been recently proposed to combat clinically relevant biofilms such as dental biofilmms, ventilator associated pneumonia, chronic wound infections, oral candidiasis, and chronic rhinosinusitis and a brief section provides suggestions for future research.
Journal ArticleDOI
Antimicrobial blue light inactivation of pathogenic microbes: State of the art.
Yucheng Wang,Ying Wang,Yuguang Wang,Clinton K. Murray,Michael R. Hamblin,David C. Hooper,Tianhong Dai +6 more
TL;DR: An updated overview of the findings from the new studies over the past 5 years is provided, including the efficacy of antimicrobial blue light inactivation of different microbes, its mechanism of action, synergism of antim antibiotic blue light with other angents, its effect on host cells and tissues, the potential development of resistance to antimicrobialblue light by microbes, and a novel interstitial delivery approach of antimacterial blue light.
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Photobiomodulation (blue and green light) encourages osteoblastic-differentiation of human adipose-derived stem cells: role of intracellular calcium and light-gated ion channels.
TL;DR: In this article, the effects of delivering four different wavelengths at the same dose (3.5 J/cm2) five times (every two days) on human adipose-derived stem cells (hASCs) cultured in osteogenic medium over three weeks were examined.
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Photobiomodulation of human adipose-derived stem cells using 810nm and 980nm lasers operates via different mechanisms of action.
TL;DR: It is concluded that 980nm affects temperature-gated calcium ion channels, while 810nm largely affects mitochondrial cytochrome c oxidase.
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Red (660 nm) or near-infrared (810 nm) photobiomodulation stimulates, while blue (415 nm), green (540 nm) light inhibits proliferation in human adipose-derived stem cells.
TL;DR: The data suggest that blue/green light inhibits proliferation by activating TRPV1, and increasing calcium and ROS.