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Yuko Kato
Researcher at University of Tokyo
Publications - 20
Citations - 1119
Yuko Kato is an academic researcher from University of Tokyo. The author has contributed to research in topics: Catalysis & Schiff base. The author has an hindex of 10, co-authored 20 publications receiving 1097 citations.
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Journal ArticleDOI
Bioactive marine metabolites. Part 16. Calyculin A. A novel antitumor metabolite from the marine sponge Discodermia calyx
Yuko Kato,Nobuhiro Fusetani,Shigeki Matsunaga,Kanehisa Hashimoto,Shigeo Fujita,Toshio Furuya +5 more
Journal ArticleDOI
A Homodinuclear Mn(III)2−Schiff Base Complex for Catalytic Asymmetric 1,4-Additions of Oxindoles to Nitroalkenes
Yuko Kato,Makoto Furutachi,Zhihua Chen,Harunobu Mitsunuma,Shigeki Matsunaga,Masakatsu Shibasaki +5 more
TL;DR: Catalytic asymmetric 1,4-additions of 3-substituted oxindoles to beta-aryl, beta-heteroaryl, and beta-alkenyl nitroalkenes are described, providing useful chiral building blocks for the synthesis of beta-aminooxindoles with vicinal quaternary/tertiary carbon stereocenters.
Journal Article
Calyculin A, an Inhibitor of Protein Phosphatases, a Potent Tumor Promoter on CD-1 Mouse Skin
Masami Suganuma,Hirota Fujiki,Hiroko Furuya-Suguri,Shigeru Yoshizawa,Shigeru Yasumoto,Yuko Kato,Nobuhiro Fusetani,Takashi Sugimura +7 more
TL;DR: Calyculin A, isolated from a marine sponge, has a novel spiro ketal skeleton and is the first tumor promoter to be screened by the okadaic acid receptor binding test, and is an additional member of the okADAic acid class of tumor promoters.
Journal ArticleDOI
Bioactive marine metabolites. 24. Isolation and structure elucidation of calyculins B, C, and D, novel antitumor metabolites, from the marine sponge Discodermia calyx
TL;DR: Calyculins B, C, and D and the previously reported calyculin A, potent antitumor metabolites, have been isolated from the Japanese sponge Discodermia calyx as mentioned in this paper.
Journal ArticleDOI
Calyculin-A increases the level of protein phosphorylation and changes the shape of 3T3 fibroblasts.
Lynn Chartier,Lucinda L. Rankin,Ronald E. Allen,Yuko Kato,Nobuhiro Fusetani,Hideaki Karaki,Shugo Watabe,David J. Hartshorne +7 more
TL;DR: Calyculin-A, an inhibitor of type 1 and 2A phosphatases, was applied extracellularly to 3T3 fibroblasts adding further support to the idea that cell shape is controlled, at least in part, by concerted actions of a kinase-phosphatase couple.