Y
Yun Wu
Researcher at State University of New York System
Publications - 83
Citations - 3073
Yun Wu is an academic researcher from State University of New York System. The author has contributed to research in topics: Cancer & Exosome. The author has an hindex of 26, co-authored 74 publications receiving 2332 citations. Previous affiliations of Yun Wu include National Institute of Standards and Technology & Pfizer.
Papers
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Journal ArticleDOI
Nanochannel electroporation delivers precise amounts of biomolecules into living cells
Pouyan E. Boukany,Andrew Morss,Wei Ching Liao,Brian E. Henslee,Hyunchul Jung,Xulang Zhang,Bo Yu,Xinmei Wang,Yun Wu,Lei Li,Keliang Gao,Xin Hu,Xi Zhao,Orin Hemminger,Wu Lu,Gregory P. Lafyatis,L. James Lee +16 more
TL;DR: It is shown that nanochannel electroporation can deliver precise amounts of a variety of transfection agents into living cells, and is expected to have high-throughput delivery applications.
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Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer
Yun Wu,Melissa Crawford,Yicheng Mao,Robert J. Lee,Ian C. Davis,Terry S. Elton,L. James Lee,Serge P. Nana-Sinkam +7 more
TL;DR: The cationic lipoplexes (LPs)-based carrier that efficiently delivered miR-29b and efficiently reduced the expression of key targets CDK6, DNMT3B, and myeloid cell leukemia sequence 1 (MCL1), as well as cell growth and clonogenicity of A549 cells.
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MicroRNA Delivery by Cationic Lipoplexes for Lung Cancer Therapy
TL;DR: Cationic lipoplexes are a promising carrier system for the development of miRNA-based therapeutics in lung cancer treatment and demonstrated that cationic lipid based miRNA delivery system to address some of these challenges.
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FcγRIIb on Liver Sinusoidal Endothelium Clears Small Immune Complexes
Latha P. Ganesan,Jonghan Kim,Yun Wu,Sudhasri Mohanty,Gary Phillips,Daniel J. Birmingham,John M. Robinson,Clark L. Anderson +7 more
TL;DR: RIIb on LSEC, a major scavenger, keeps SIC blood concentrations low and minimizes pathologic deposition of inflammatory immune complex, thereby controlling immune complex-mediated autoimmune disease.
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Metabolic reprogramming of stromal fibroblasts by melanoma exosome microRNA favours a pre-metastatic microenvironment.
Shin La Shu,Yunchen Yang,Cheryl Allen,Orla Maguire,Hans Minderman,Arindam Sen,Michael J. Ciesielski,Katherine A. Collins,Peter J. Bush,Prashant Singh,Xue Wang,Martin Morgan,Jun Qu,Richard B. Bankert,Theresa L. Whiteside,Yun Wu,Marc S. Ernstoff +16 more
TL;DR: The data indicate that melanoma-derived exosomes modulate stromal cell metabolism and may contribute to the creation of a pre-metastatic niche that promotes the development of metastasis.