Y
Yung-Hsin Yeh
Researcher at Chang Gung University
Publications - 44
Citations - 2825
Yung-Hsin Yeh is an academic researcher from Chang Gung University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 27 publications receiving 2548 citations. Previous affiliations of Yung-Hsin Yeh include Université de Montréal & Montreal Heart Institute.
Papers
More filters
Journal ArticleDOI
Arrhythmogenic Ion-Channel Remodeling in the Heart: Heart Failure, Myocardial Infarction, and Atrial Fibrillation
TL;DR: The changes in ion channel and transporter properties associated with three important clinical and experimental paradigms: congestive heart failure, myocardial infarction, and atrial fibrillation are reviewed and important opportunities for improved therapeutic approaches are highlighted.
Journal ArticleDOI
Calcium-Handling Abnormalities Underlying Atrial Arrhythmogenesis and Contractile Dysfunction in Dogs With Congestive Heart Failure
Yung-Hsin Yeh,Reza Wakili,Xiao-Yan Qi,Denis Chartier,Peter Boknik,Stefan Kääb,Ursula Ravens,Pierre Coutu,Dobromir Dobrev,Stanley Nattel +9 more
TL;DR: Congestive heart failure causes profound changes in Ca2-handling and -regulatory proteins that produce atrial fibrillation–promoting atrial cardiomyocyte Ca2+-handing abnormalities, arrhythmogenic triggered activity, and contractile dysfunction.
Journal ArticleDOI
Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia.
Kristina Lemola,Denis Chartier,Yung-Hsin Yeh,Marc Dubuc,Raymond Cartier,Andrew Armour,Michael Ting,Masao Sakabe,Akiko Shiroshita-Takeshita,Philippe Comtois,Stanley Nattel +10 more
TL;DR: Intact PVs are not needed for maintenance of experimental cholinergic AF and ablation of the autonomic ganglia at the base of the PVs suppresses vagal responses and may contribute to the effectiveness of PV-directed ablation procedures in vagal AF.
Journal ArticleDOI
Changes in Connexin Expression and the Atrial Fibrillation Substrate in Congestive Heart Failure
Brett Burstein,Philippe Comtois,Georghia Michael,Kunihiro Nishida,Louis Villeneuve,Yung-Hsin Yeh,Stanley Nattel +6 more
TL;DR: CHF causes atrial connexin changes, but these are not essential for CHF-related conduction disturbances and AF promotion, which are rather related primarily to fibrotic interruption of muscle bundle continuity.
Journal ArticleDOI
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current
Xiao Yan Qi,Yung-Hsin Yeh,Yung-Hsin Yeh,Ling Xiao,Ling Xiao,Brett Burstein,Ange Maguy,Denis Chartier,Louis Villeneuve,Bianca J. J. M. Brundel,Dobromir Dobrev,Stanley Nattel,Stanley Nattel,Stanley Nattel +13 more
TL;DR: Rapid atrial cardiomyocyte activation causes Ca2+ loading, which activates the Ca2-dependent calmodulin–calcineurin–NFAT system to cause transcriptional downregulation of ICaL, restoring Ca 2+i to normal at the cost of APD reduction.