R
Reza Wakili
Researcher at University of Duisburg-Essen
Publications - 101
Citations - 2808
Reza Wakili is an academic researcher from University of Duisburg-Essen. The author has contributed to research in topics: Atrial fibrillation & Medicine. The author has an hindex of 22, co-authored 80 publications receiving 2141 citations. Previous affiliations of Reza Wakili include Ludwig Maximilian University of Munich & Université de Montréal.
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Journal ArticleDOI
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
Patrick T. Ellinor,Kathryn L. Lunetta,Christine M. Albert,Christine M. Albert,Nicole L. Glazer,Marylyn D. Ritchie,Albert V. Smith,Dan E. Arking,Martina Müller-Nurasyid,Bouwe P. Krijthe,Steven A. Lubitz,Steven A. Lubitz,Joshua C. Bis,Mina K. Chung,Mina K. Chung,Marcus Dörr,Kouichi Ozaki,Jason D. Roberts,J. Gustav Smith,J. Gustav Smith,Arne Pfeufer,Moritz F. Sinner,Moritz F. Sinner,Moritz F. Sinner,Kurt Lohman,Jingzhong Ding,Nicholas L. Smith,Jonathan D. Smith,Jonathan D. Smith,Michiel Rienstra,Kenneth Rice,David R. Van Wagoner,David R. Van Wagoner,Jared W. Magnani,Reza Wakili,Sebastian Clauss,Jerome I. Rotter,Gerhard Steinbeck,Lenore J. Launer,Robert W. Davies,Matthew Borkovich,Tamara B. Harris,Honghuang Lin,Uwe Völker,Henry Völzke,David J. Milan,Albert Hofman,Eric Boerwinkle,Lin Y. Chen,Elsayed Z. Soliman,Benjamin F. Voight,Guo Li,Aravinda Chakravarti,Michiaki Kubo,Usha B. Tedrow,Usha B. Tedrow,Lynda M. Rose,Paul M. Ridker,Paul M. Ridker,David Conen,Tatsuhiko Tsunoda,Tetsushi Furukawa,Nona Sotoodehnia,Siyan Xu,Naoyuki Kamatani,Daniel Levy,Yusuke Nakamura,Babar Parvez,Saagar Mahida,Karen L. Furie,Jonathan Rosand,Raafia Muhammad,Bruce M. Psaty,Thomas Meitinger,Siegfried Perz,H-Erich Wichmann,Jacqueline C.M. Witteman,W. H. Linda Kao,Sekar Kathiresan,Sekar Kathiresan,Dan M. Roden,André G. Uitterlinden,Fernando Rivadeneira,Barbara McKnight,Marketa Sjögren,Anne B. Newman,Yongmei Liu,Michael H. Gollob,Olle Melander,Toshihiro Tanaka,Bruno H. Stricker,Stephan B. Felix,Alvaro Alonso,Dawood Darbar,John Barnard,Daniel I. Chasman,Daniel I. Chasman,Susan R. Heckbert,Susan R. Heckbert,Emelia J. Benjamin,Vilmundur Gudnason,Stefan Kääb +101 more
TL;DR: Six new atrial fibrillation susceptibility loci implicate candidate genes that encode transcription factors related to cardiopulmonary development, cardiac-expressed ion channels and cell signaling molecules that are associated with stroke, heart failure and death.
Journal ArticleDOI
Calcium-Handling Abnormalities Underlying Atrial Arrhythmogenesis and Contractile Dysfunction in Dogs With Congestive Heart Failure
Yung-Hsin Yeh,Reza Wakili,Xiao-Yan Qi,Denis Chartier,Peter Boknik,Stefan Kääb,Ursula Ravens,Pierre Coutu,Dobromir Dobrev,Stanley Nattel +9 more
TL;DR: Congestive heart failure causes profound changes in Ca2-handling and -regulatory proteins that produce atrial fibrillation–promoting atrial cardiomyocyte Ca2+-handing abnormalities, arrhythmogenic triggered activity, and contractile dysfunction.
Journal ArticleDOI
Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations.
Charlotte Glinge,Sebastian Clauss,Kim Boddum,Reza Jabbari,Javad Jabbari,Bjarke Risgaard,Philipp Tomsits,Bianca Hildebrand,Stefan Kääb,Reza Wakili,Thomas Jespersen,Jacob Tfelt-Hansen +11 more
TL;DR: This study highlights the importance of proper and systematic sample collection and preparation when measuring circulating miRNAs, e.g., in context of clinical trials and demonstrated that the type of collection tubes, preparation, handling and storage of samples should be standardized to avoid confounding variables influencing the results.
Journal ArticleDOI
Mechanisms of Atrial Tachyarrhythmias Associated With Coronary Artery Occlusion in a Chronic Canine Model
Kunihiro Nishida,Xiao Yan Qi,Reza Wakili,Reza Wakili,Philippe Comtois,Denis Chartier,Masahide Harada,Yu Ki Iwasaki,Philippe Romeo,Ange Maguy,Dobromir Dobrev,Georghia Michael,Mario Talajic,Stanley Nattel +13 more
TL;DR: Chronic atrial infarction in dogs promotes both AF triggers and the substrate for AF maintenance, and novel insights into potential AF mechanisms in patients with coronary artery disease are provided.
Journal ArticleDOI
Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment
Larissa Fabritz,Eduard Guasch,Charalambos Antoniades,Isabel Bardinet,Gerlinde Benninger,Timothy R. Betts,Eva Brand,Günter Breithardt,Gabriela Bucklar-Suchankova,A. John Camm,A. John Camm,David Cartlidge,Barbara Casadei,Winnie Chua,Harry J.G.M. Crijns,Jon Deeks,Stéphane N. Hatem,Françoise Hidden-Lucet,Stefan Kääb,Nikos Maniadakis,Stephan Martin,Lluís Mont,Holger Reinecke,Moritz F. Sinner,Ulrich Schotten,Taunton R. Southwood,Monika Stoll,Panos E. Vardas,Reza Wakili,Andrew West,André Ziegler,Paulus Kirchhof +31 more
TL;DR: A roadmap to develop a set of clinical markers that reflect the major causes of AF in patients is proposed to transform the insights into the mechanisms causing AF into a format that can underpin future personalized strategies to prevent and treat AF, ultimately informing better patient care.