Yvonne McGrath

TL;DR: Four new reagents termed immune-mobilizing monoclonal TCRs against cancer (ImmTACs) effectively redirected T cells to kill cancer cells expressing extremely low surface epitope densities and suppressed tumor growth in vivo.

TL;DR: In this paper, it was shown that the virion host shutoff protein (vhs) plays a key role in the inactivation of dendritic cells and is therefore likely to be important for immune evasion by the virus.

TL;DR: Data support a pathogenetic model of HSV infection, in which initial delay in the generation of immune responses to HSV at peripheral sites is mediated by disruption of DC function but is overcome by bystander DC maturation and cross-presentation ofHSV antigens.

TL;DR: Results indicate that HSV-1-infected mature DCs are limited in their capacity to migrate to secondary lymphoid organs, the areas of antigen presentation and T-cell stimulation, thus inhibiting an antiviral immune response.