Z
Zhen Yang
Researcher at Chinese PLA General Hospital
Publications - 16
Citations - 356
Zhen Yang is an academic researcher from Chinese PLA General Hospital. The author has contributed to research in topics: Regeneration (biology) & Mesenchymal stem cell. The author has an hindex of 5, co-authored 16 publications receiving 66 citations. Previous affiliations of Zhen Yang include Nankai University.
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Journal ArticleDOI
Enhancement of acellular cartilage matrix scaffold by Wharton's jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration
Shuangpeng Jiang,Shuangpeng Jiang,Guangzhao Tian,Guangzhao Tian,Zhen Yang,Zhen Yang,Xiang Gao,Fuxin Wang,Juntan Li,Zhuang Tian,Bo Huang,Fu Wei,Xinyu Sang,Liuqi Shao,Zhou Jian,Zhenyong Wang,Shuyun Liu,Xiang Sui,Quanyi Guo,Weimin Guo,Xu Li +20 more
TL;DR: Wang et al. as mentioned in this paper showed that Wharton's jelly exosomes can promote the migration and proliferation of bone marrow-derived mesenchymal stem cells (MSC-Exos) and the proliferation of chondrocytes.
Journal ArticleDOI
Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application.
Kangkang Zha,Kangkang Zha,Xu Li,Zhen Yang,Zhen Yang,Guangzhao Tian,Guangzhao Tian,Zhiqiang Sun,Zhiqiang Sun,Xiang Sui,Dai Yongjing,Shuyun Liu,Quanyi Guo +12 more
TL;DR: In this article, the heterogeneity of MSCs at the donor, tissue source and cell immunophenotype levels, including their cytological properties, such as their ability for proliferation, chondrogenic differentiation and immunoregulation, were discussed.
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3D-Bioprinted Difunctional Scaffold for In Situ Cartilage Regeneration Based on Aptamer-Directed Cell Recruitment and Growth Factor-Enhanced Cell Chondrogenesis.
Zhen Yang,Zhen Yang,Tianyuan Zhao,Tianyuan Zhao,Cangjian Gao,Cangjian Gao,Fuyang Cao,Fuyang Cao,Hao Li,Hao Li,Zhiyao Liao,Zhiyao Liao,Liwei Fu,Liwei Fu,Pinxue Li,Pinxue Li,Wei Chen,Wei Chen,Zhiqiang Sun,Zhiqiang Sun,Shuangpeng Jiang,Zhuang Tian,Guangzhao Tian,Guangzhao Tian,Kangkang Zha,Kangkang Zha,Tingting Pan,Xu Li,Xiang Sui,Zhiguo Yuan,Shuyun Liu,Quanyi Guo,Quanyi Guo +32 more
TL;DR: In this article, a 3D-bioprinted difunctional scaffold was developed based on aptamer HM69-mediated MSC-specific recruitment and growth factor-enhanced cell chondrogenesis.
Journal ArticleDOI
Advances and prospects in biomimetic multilayered scaffolds for articular cartilage regeneration.
Liwei Fu,Liwei Fu,Zhen Yang,Zhen Yang,Cangjian Gao,Cangjian Gao,Hao Li,Hao Li,Zhiguo Yuan,Zhiguo Yuan,Fuxin Wang,Xiang Sui,Shuyun Liu,Quanyi Guo,Quanyi Guo +14 more
TL;DR: This review focuses on the current status of multilayered scaffolds developed for AC defect repair, including design strategies based on the degree of defect severity and the zone-specific characteristics of AC tissue, the selection and composition of biomaterials, and techniques for design and manufacturing.
Journal ArticleDOI
Research Progress on Stem Cell Therapies for Articular Cartilage Regeneration.
Shuangpeng Jiang,Shuangpeng Jiang,Guangzhao Tian,Guangzhao Tian,Xu Li,Zhen Yang,Zhen Yang,Fuxin Wang,Zhuang Tian,Bo Huang,Fu Wei,Kangkang Zha,Kangkang Zha,Zhiqiang Sun,Zhiqiang Sun,Xiang Sui,Shuyun Liu,Weimin Guo,Weimin Guo,Quanyi Guo +19 more
TL;DR: A review of the latest developments in these areas, summarize challenges in articular cartilage regeneration strategies involving stem cells, and describe prospects for future development can be found in this paper.