Z
Zhenbiao Wu
Researcher at Fourth Military Medical University
Publications - 39
Citations - 700
Zhenbiao Wu is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 29 publications receiving 583 citations.
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Journal ArticleDOI
Role of the frequency of blood CD4(+) CXCR5(+) CCR6(+) T cells in autoimmunity in patients with Sjögren's syndrome.
TL;DR: In this article, the frequency of CD4+ CXCR5+ T cells is increased in pSS patients and positively correlated with autoantibodies in the blood, and the concentration of Th17-like subsets was found to be significantly higher than in healthy controls.
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Targeting radioimmunotherapy of hepatocellular carcinoma with iodine (131I) metuximab injection : Clinical phase I/II trials
Zhi-Nan Chen,Li Mi,Jing Xu,Fei Song,Qing Zhang,Zheng Zhang,Jinliang Xing,Huijie Bian,Jian-Li Jiang,Xian-Hui Wang,Peng Shang,Airong Qian,Sihe Zhang,Ling Li,Yu Li,Qiang Feng,Xiao-Ling Yu,Yuan Feng,Xiang-Min Yang,Rong Tian,Zhenbiao Wu,Nan Leng,Tingshu Mo,Anren Kuang,Tianzhi Tan,Yunchun Li,De-Rong Liang,Wusheng Lu,Jia Miao,Guo-Hui Xu,Zhi-Hui Zhang,Kejun Nan,Han Jun,Qing-Guang Liu,Hongxin Zhang,Ping Zhu +35 more
TL;DR: Iodine (131I) metuximab injection is safe and active for HCC patients and was found to be targeted and concentrated to tumor tissues in the Phase II trial.
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CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes.
TL;DR: The studies demonstrated that the CD147 overexpression on monocytes/macrophages and FLS in RA patients may be responsible for the enhanced MMP secretion and activation and for the invasiveness of synoviocytes, suggesting that CD147 may be one of the important factors in progressive joint destruction of RA.
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Treatment of foot disease in patients with type 2 diabetes mellitus using human umbilical cord blood mesenchymal stem cells: response and correction of immunological anomalies.
Xiao-Yan Li,Zhaohui Zheng,Xueyi Li,Jian Guo,Yan Zhang,Hui Li,Yang-Wei Wang,Jun Ren,Zhenbiao Wu +8 more
TL;DR: Level of blood glucose and required insulin dosage were reduced after hUCB-MSC transplantation accompanied with improved clinical profiles in diabetic patients, indicating a role for Treg cells in the onset and progression of T2D.
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Long-term culture in vitro impairs the immunosuppressive activity of mesenchymal stem cells on T cells.
TL;DR: The morphology of MSCs showed the typical characteristics of the Hayflick model of cellular aging during sequential expansion during sequential passage, and the immunosuppressive effects of M SCs on the allogeneic T-cell proliferation, activation-antigen and cytokine production were significantly impaired following stimulation with phytohemagglutinin.