L
Ling Li
Researcher at Peking Union Medical College
Publications - 73
Citations - 3828
Ling Li is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 19, co-authored 63 publications receiving 2425 citations. Previous affiliations of Ling Li include Fourth Military Medical University & Henan University.
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Journal ArticleDOI
Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial.
Ling Li,Zhang Wei,Yu Hu,Xunliang Tong,Shangen Zheng,Juntao Yang,Yujie Kong,Lili Ren,Qing Wei,Heng Mei,Caiying Hu,Cuihua Tao,Ru Yang,Jue Wang,Yongpei Yu,Guo Yong,Xiaoxiong Wu,Zhihua Xu,Li Zeng,Nian Xiong,Lifeng Chen,Juan Wang,Ning Man,Yu Liu,Haixia Xu,E. Deng,Xuejun Zhang,Chenyue Li,Conghui Wang,Shisheng Su,Linqi Zhang,Jianwei Wang,Yanyun Wu,Zhong Liu +33 more
TL;DR: Among patients with severe or life-threatening COVID-19, convalescent plasma therapy added to standard treatment, compared with standard treatment alone, did not result in a statistically significant improvement in time to clinical improvement within 28 days.
Journal ArticleDOI
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells.
Ke Wang,Wei Chen,Zheng Zhang,Yong-Qiang Deng,Jian-Qi Lian,Peng Du,Ding Wei,Yang Zhang,Xiu-Xuan Sun,Li Gong,Xu Yang,Lei He,Lei Zhang,Zhiwei Yang,Jie-Jie Geng,Ruo Chen,Zhang Hai,Bin Wang,Yu-Meng Zhu,Gang Nan,Jian-Li Jiang,Ling Li,Jiao Wu,Peng Lin,Wan Huang,Liangzhi Xie,Zhaohui Zheng,Kui Zhang,Jinlin Miao,Hong-Yong Cui,Min Huang,Jun Zhang,Ling Fu,Xiang-Min Yang,Zhongpeng Zhao,Shihui Sun,Hongjing Gu,Zhe Wang,Chun-Fu Wang,Yacheng Lu,Liu Yingying,Qing-Yi Wang,Huijie Bian,Ping Zhu,Zhi-Nan Chen +44 more
TL;DR: A novel virus entry route, CD147-spike protein, is revealed, which provides an important target for developing specific and effective drug against COVID-19.
Journal ArticleDOI
Function of HAb18G/CD147 in Invasion of Host Cells by Severe Acute Respiratory Syndrome Coronavirus
Zhi-Nan Chen,Li Mi,Jing Xu,Jiyun Yu,Xian-Hui Wang,Jian-Li Jiang,Jinliang Xing,Peng Shang,Airong Qian,Yu Li,Peter X. Shaw,Jianwei Wang,Shumin Duan,Jin Ding,Chun-Mei Fan,Yang Zhang,Yong Yang,Xiao-Ling Yu,Qiang Feng,Biehu Li,Xi-ying Yao,Zheng Zhang,Ling Li,Xiaoping Xue,Ping Zhu +24 more
TL;DR: Results show that HAb18G/CD147, mediated by CyPA bound to SARS-CoV N protein, plays a functional role in facilitating invasion of host cells by SARS -CoV.
Journal ArticleDOI
CNSA: a data repository for archiving omics data.
Xueqin Guo,Fengzhen Chen,Fei Gao,Ling Li,Ke Liu,Lijin You,Cong Hua,Fan Yang,Wanliang Liu,Chunhua Peng,Lina Wang,Xiaoxia Yang,Feiyu Zhou,Jiawei Tong,Jia Cai,Zhiyong Li,Bo Wan,Lei Zhang,Tao Yang,Minwen Zhang,Linlin Yang,Yawen Yang,Wenjun Zeng,Bo Wang,Xiaofeng Wei,Xun Xu +25 more
TL;DR: CNGB Sequence Archive (CNSA) is presented for archiving omics data, including raw sequencing data and its further analyzed results which are organized into six objects, namely Project, Sample, Experiment, Run, Assembly and Variation at present.
Journal ArticleDOI
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation.
Jing Xu,Zhong-Yang Shen,Xin-Guo Chen,Qing Zhang,Huijie Bian,Ping Zhu,Huiyun Xu,Fei Song,Xiang-Min Yang,Li Mi,Qing-Chuan Zhao,Rong Tian,Qiang Feng,Sihe Zhang,Yu Li,Jian-Li Jiang,Ling Li,Xiao-Ling Yu,Zheng Zhang,Zhi-Nan Chen +19 more
TL;DR: Licartin is a promising drug for preventing post‐OLT tumor recurrence in advanced HCC patients excluded by the currently strict criteria for OLT, and can be a good drug target.