J
Jinliang Xing
Researcher at Fourth Military Medical University
Publications - 160
Citations - 5416
Jinliang Xing is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Cancer & Single-nucleotide polymorphism. The author has an hindex of 37, co-authored 142 publications receiving 4025 citations. Previous affiliations of Jinliang Xing include University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Mitochondrial DNA Content: Its Genetic Heritability and Association With Renal Cell Carcinoma
Jinliang Xing,Meng Chen,Christopher G. Wood,Jie Lin,Margaret R. Spitz,Jianzhong Ma,Christopher I. Amos,Peter G. Shields,Neal L. Benowitz,Jian Gu,Mariza de Andrade,Gary E. Swan,Xifeng Wu +12 more
TL;DR: In this article, the mtDNA content appears to have high heritability and a statistically significant dose-response relationship was detected between lower mtDNA contents and an increased risk of renal cell carcinoma.
Journal ArticleDOI
Function of HAb18G/CD147 in Invasion of Host Cells by Severe Acute Respiratory Syndrome Coronavirus
Zhi-Nan Chen,Li Mi,Jing Xu,Jiyun Yu,Xian-Hui Wang,Jian-Li Jiang,Jinliang Xing,Peng Shang,Airong Qian,Yu Li,Peter X. Shaw,Jianwei Wang,Shumin Duan,Jin Ding,Chun-Mei Fan,Yang Zhang,Yong Yang,Xiao-Ling Yu,Qiang Feng,Biehu Li,Xi-ying Yao,Zheng Zhang,Ling Li,Xiaoping Xue,Ping Zhu +24 more
TL;DR: Results show that HAb18G/CD147, mediated by CyPA bound to SARS-CoV N protein, plays a functional role in facilitating invasion of host cells by SARS -CoV.
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Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Qichao Huang,Lei Zhan,Haiyan Cao,Jibin Li,Yinghua Lyu,Xu Guo,Jing Zhang,Lele Ji,Tingting Ren,Jiaze An,Bingrong Liu,Yongzhan Nie,Jinliang Xing +12 more
TL;DR: It is demonstrated that increased mitochondrial fission plays a critical role in regulation of HCC cell survival, which provides a strong evidence for this process as drug target in HCC treatment.
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CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways.
Jibin Li,Qichao Huang,Xiaoyu Long,Jing Zhang,Xiaojun Huang,Jiye Aa,Hushan Yang,Zhi-Nan Chen,Jinliang Xing +8 more
TL;DR: It is demonstrated that CD147 is a critical regulator of fatty acid metabolism, which provides a strong line of evidence for this molecule to be used as a drug target in cancer treatment.
Journal ArticleDOI
Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells
Yibing Chen,Yanjun Mi,Xiaofei Zhang,Qian Ma,Yucen Song,Liwei Zhang,Dandan Wang,Jinliang Xing,Benxin Hou,Haolong Li,Huan Jin,Wei Du,Zhengzhi Zou +12 more
TL;DR: Data suggested that ferroptosis might be a novel anticancer mechanism of DHA in glioma and HSPA5 may serve as a negative regulator of D HA-induced ferroPTosis.