Z
Zhengrong Guan
Researcher at University of Alabama at Birmingham
Publications - 31
Citations - 664
Zhengrong Guan is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Afferent arterioles & Kidney. The author has an hindex of 13, co-authored 26 publications receiving 600 citations. Previous affiliations of Zhengrong Guan include University of Queensland & Georgia Regents University.
Papers
More filters
Journal ArticleDOI
Delayed administration of darbepoetin or erythropoietin protects against ischemic acute renal injury and failure.
TL;DR: The results reaffirm the potential clinical application of DPO and EPO as novel renoprotective agents for patients at risk of ischemic acute renal failure or after having sustained an isChemic renal insult.
Journal ArticleDOI
Effect of Epithelial Sodium Channel Blockade on the Myogenic Response of Rat Juxtamedullary Afferent Arterioles
TL;DR: It is suggested that ENaC may function as mechanosensitive ion channels initiating pressure-dependent myogenic responses in rat juxtamedullary afferent arterioles.
Journal ArticleDOI
Renal endothelial dysfunction and impaired autoregulation after ischemia-reperfusion injury result from excess nitric oxide
TL;DR: It is suggested that tubuloglomerular feedback is preserved in IARF but that excess NO and probably EDHF produce endothelial dysfunction and antagonize autoregulation, which is predominantly functional rather than structural.
Journal ArticleDOI
P2X receptors as regulators of the renal microvasculature
TL;DR: The implication that renal microvascular dysfunction in disease is related to P2 receptor dysfunction is considered and some important issues and challenges that require further attention are highlighted.
Journal ArticleDOI
Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
Xingsheng Li,John Knight,Sonia Fargue,Brianna Buchalski,Zhengrong Guan,Edward W. Inscho,Abigail Liebow,Kevin Fitzgerald,William Querbes,W. Todd Lowther,Ross P. Holmes +10 more
TL;DR: The results suggest that siRNA approaches could be useful for decreasing the oxalate burden on the kidney in individuals with Primary Hyperoxaluria.