X
Xiao-Ying Xu
Researcher at Chinese Academy of Sciences
Publications - 183
Citations - 4113
Xiao-Ying Xu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 34, co-authored 183 publications receiving 3607 citations. Previous affiliations of Xiao-Ying Xu include University of Science and Technology of China.
Papers
More filters
Journal ArticleDOI
Highly Enantioselective Organocatalytic Biginelli Reaction
TL;DR: A new chiral phosphoric acid, derived from 3,3'-diphenyl-H8-binol, exhibited superior catalytic activity and enantioselectivity compared to its structural analogues, affording high enantiOSElectivities ranging from 85 to 97% ee with a wide scope of substrates.
Journal ArticleDOI
Asymmetric Organocatalytic Biginelli Reactions: A New Approach To Quickly Access Optically Active 3,4-Dihydropyrimidin-2-(1H)-ones
TL;DR: Developments in the synthetic methods to access optically active DHPMs are summarized with an emphasis on the recent advances in the asymmetric catalytic Biginelli reactions, along with concepts to design the organocatalytic asymmetric variants.
Journal ArticleDOI
Design of organocatalysts for asymmetric direct syn-aldol reactions
TL;DR: Two new organocatalysts 3a and 3b, derived from L-leucine and (S)-beta-amino alcohols, were designed and afforded the direct syn-aldol reactions of a wide scope of aldehydes with various ketones with an excellent diastereomeric ratio of up to >20/1 and enantioselectivities ofup to 99% ee.
Journal ArticleDOI
Asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and 3-nitroindoles with amino-thiocarbamate catalysts: enantioselective synthesis of polycyclic spirooxindoles.
Jian-Qiang Zhao,Ming-Qiang Zhou,Zhi-Jun Wu,Zhen-Hua Wang,Deng-Feng Yue,Xiao-Ying Xu,Xiao-Mei Zhang,Wei-Cheng Yuan +7 more
TL;DR: An unprecedented organocatalytic asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and 3-nitroindoles has been disclosed and a wide range of enantioenriched polycyclic spirooxindoles, containing three contiguous chiral centers with two of them having quaternary stereocenters are obtained.
Journal ArticleDOI
Organocatalytic stereocontrolled synthesis of 3,3′-pyrrolidinyl spirooxindoles by [3+2] annulation of isocyanoesters with methyleneindolinones
Liang-Liang Wang,Jian-Fei Bai,Lin Peng,Liang-Wen Qi,Li-Na Jia,Yun-Long Guo,Xi-Ya Luo,Xiao-Ying Xu,Li-Xin Wang +8 more
TL;DR: A stereoselective [3+2] cycloaddition of isocyanoesters to methyleneindolinones catalyzed by a quinine-based thiourea-tertiary amine has been successfully developed and a variety of optically enriched 3,3'-pyrrolidinyl spirooxindole diastereomers could be obtained in excellent enantioselectivities.