Z
Zhigang Zhang
Researcher at Shanghai Jiao Tong University
Publications - 335
Citations - 13480
Zhigang Zhang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 48, co-authored 281 publications receiving 9429 citations. Previous affiliations of Zhigang Zhang include Chongqing University & Chinese Academy of Sciences.
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Mechanical performance of high-strength engineering cementitious composites (ECC) with hybriding PE and steel fibers
TL;DR: In this article , the mechanical performance of high-strength ECC with hybriding steel and PE fibers was investigated experimentally; meanwhile, the effects of ultra-fine fly ash and crumb rubber on the properties of HF-ECC were also researched.
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17-allylamino-17-(demethoxy)geldanamycin (17-AAG) is a potent and effective inhibitor of human cytomegalovirus replication in primary fibroblast cells
TL;DR: The data suggested a mechanism of action where 17-AAG blocked immediate-early protein transactivation and three molecular targets may explain the antiviral activities of this compound.
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Single-cell RNA sequencing reveals that targeting HSP90 suppresses PDAC progression by restraining mitochondrial bioenergetics.
Li-Peng Hu,Kai-Xia Zhou,Yan-Miao Huo,De-Jun Liu,Qing Li,Min-Wei Yang,Pei-Qi Huang,Chunjie Xu,Guang-Ang Tian,Lin-Li Yao,Xueli Zhang,Ya-Hui Wang,Jun Li,Zhigang Zhang,Shu-Heng Jiang,Xin Xing,Xu Wang,Wei-Ting Qin,Qin Yang +18 more
TL;DR: Zhang et al. as mentioned in this paper performed single-cell RNA sequencing to characterize pancreatic ductal adenocarcinoma (PDAC) tumors from KPC mice and found that PDAC cluster 2 cells with highly Hsp90 expression is much more aggressive than the other clusters.
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Experimental Study on Damage Detection in ECC-Concrete Composite Beams Using Piezoelectric Transducers.
TL;DR: An electromechanical impedance-based technique is used to monitor the structural damage of RC beams strengthened with an ECC layer at the tensile zone and shows the damage location can be derived from the measured conductance signatures of an array of PZT transducers.
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Terbinafine prevents colorectal cancer growth by inducing dNTP starvation and reducing immune suppression.
Li-Peng Hu,Wuqing Huang,Xu Wang,Chunjie Xu,Wei Qin,Dongxue Li,Guang-Ang Tian,Qing Li,Yao-Qi Zhou,Suyuan Chen,Huizhen Nie,Yujun Hao,Jian Song,Xueli Zhang,J. Lundquist,Kristina Sundquist,Jun Li,Shu-Heng Jiang,Zhigang Zhang,Jianguang Ji +19 more
TL;DR: In this article , the authors explored whether reversing the fungal dysbiosis by terbinafine, an approved antifungal drug, might inhibit the development of colorectal cancer.