Z
Zhipu Luo
Researcher at Argonne National Laboratory
Publications - 49
Citations - 1179
Zhipu Luo is an academic researcher from Argonne National Laboratory. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 15, co-authored 39 publications receiving 811 citations. Previous affiliations of Zhipu Luo include Chinese Academy of Sciences & Soochow University (Suzhou).
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Journal ArticleDOI
Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy.
Yaowang Li,Chunyu Zhao,Feng Luo,Zhenying Liu,Xinrui Gui,Zhipu Luo,Xiang Zhang,Dan Li,Cong Liu,Xueming Li +9 more
TL;DR: This study provides molecular insight into the fibrillar assembly of α-syn at the atomic level and sheds light on the molecular pathogenesis caused by familial PD mutations ofα-syn.
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Structural mechanism of ring-opening reaction of glucose by human serum albumin
TL;DR: Two protein crystal structures of HSA in complex with either glucose or fructose reveal the presence of linear forms of sugar for both monosaccharides and propose a mechanism for glucose ring opening involving both residues Lys-195 and Lys-199.
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Structural evidence of perfluorooctane sulfonate transport by human serum albumin.
TL;DR: The crystal structure of the HSA-PFOS complex is reported and it is shown that PFOS binds to HSA at a molar ratio of 2:1, which provides a structural mechanism to understand the retention of surfactants in human serum.
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Structural basis of ligand recognition and self-activation of orphan GPR52.
Xi Lin,Mingyue Li,Mingyue Li,Niandong Wang,Yiran Wu,Zhipu Luo,Shimeng Guo,Gye Won Han,Shaobai Li,Yang Yue,Xiaohu Wei,Xiaohu Wei,Xin Xie,Xin Xie,Yong Chen,Yong Chen,Suwen Zhao,Jian Wu,Ming Lei,Fei Xu,Fei Xu +20 more
TL;DR: New insights into the structure and function of GPR52 could improve the understanding of other self-activated GPCRs, enable the identification of endogenous and tool ligands, and guide drug discovery efforts that target GPR 52.
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Structural Basis for Recognition of Urokinase-type Plasminogen Activator by Plasminogen Activator Inhibitor-1
Zhonghui Lin,Longguang Jiang,Cai Yuan,Cai Yuan,Jan K. Jensen,Xu Zhang,Zhipu Luo,Barbara C. Furie,Bruce Furie,Peter A. Andreasen,Mingdong Huang,Mingdong Huang +11 more
TL;DR: This study lays down a foundation for understanding the specificity of PAI-1 for uPA and tPA and provides a structural basis for further functional studies.