Zhongduo Wang

TL;DR: The highly polymorphic genome of the pearl oyster is sequenced and a large set of novel proteins participating in matrix-framework formation are identified, including components similar to that found in vertebrate bones such as collagen-related VWA-containing proteins, chondroitin sulfotransferases, and regulatory elements.

TL;DR: DNA barcode sequences of 95 fish species in 86 genera of 69 families from 15 orders captured by trawl from two important fisheries regions in South China Sea provide further evidence for the reliability and accessibility of DNA barcodes for marine fish identification, and highlight their effectiveness for flagging cases needing taxonomical reexamination.

TL;DR: A quantitative analysis of WDR structures reveals that druggable binding pockets can be found on multiple surfaces of these multifaceted protein interaction platforms, which support the development of chemical probes to further interrogate WDR proteins as an emerging therapeutic target class.

TL;DR: The crystallographic models provide structural insights into the substrate binding of the SIAH family E3 ubiquitin ligases that are critically involved in regulating cancer-related pathways and suggest caution should be taken when using menadione as a specific SIAh2 inhibitor.

TL;DR: This study suggests that although DNA barcoding aims to develop species identification systems, it may also be useful in the construction of phylogenies by aiding the selection of taxa.