Recent advances on functional nucleic acid-based biosensors for detection of food contaminants.

Engineering large-scaled electrochromic semiconductor films as reproductive SERS substrates for operando investigation at the solid/liquid interfaces

Raspberry-like CuWO4 hollow spheres anchored on sulfur-doped g-C3N4 composite: An efficient electrocatalyst for selective electrochemical detection of antibiotic drug nitrofurazone.

Inner filter effect as a sensitive sensing platform for detection of nitrofurantoin using luminescent drug-based carbon nanodots.

Highly sensitive and selective fluorescence sensing of nitrofurantoin based on water-soluble copper nanoclusters.

Rapid determination of trace nitrofurantoin in cosmetics by surface enhanced Raman spectroscopy using nanoarrayed hydroxyl polystyrene‐based substrate

Rapid and accurate analysis of multiple targets in complex samples is still a big challenge in the fast detection field. Herein, we developed a rapid and accurate strategy for simultaneous quantification of trace multiple antibiotic residues in complex aquatic samples by surface-enhanced Raman scattering (SERS) using a Ti3C2Tx/DNA/Ag membrane substrate. This membrane substrate was proven to have good uniformity, reproducibility, stability, and SERS activity by a series of characterizations. Also, this substrate combined excellent electromagnetic enhancement and chemical enhancement effects, which endowed it with good sensitivity and selectivity during SERS analysis. It achieved the integration of multitarget separation, enrichment, and in situ detection, which significantly improved the selectivity, sensitivity, accuracy, and detection throughput by membrane substrate coupling with SERS for real-sample analysis. Finally, this rapid SERS analysis strategy was successfully applied to the simultaneous quantification of trace nitrofurantoin (NFT) and ofloxacin (OFX) in aquatic samples. It was observed that trace NFT and OFX were actually detected and simultaneously quantified to be 8.0-13.7 and 42.6-49.1 μg/kg in aquatic samples, respectively, with good recoveries of 88.0-107% and relative standard deviations of 0.3-5.5%. The results were verified by a traditional high-performance liquid chromatography method with relative errors of -9.8 to 5.3%. This strategy provided a methodological reference for accurate SERS quantification of multiple targets in complex samples.

Simultaneous and Accurate Quantification of Multiple Antibiotics in Aquatic Samples by Surface-Enhanced Raman Scattering Using a Ti3C2Tx/DNA/Ag Membrane Substrate.

Advanced sample preparation techniques for rapid surface-enhanced Raman spectroscopy analysis of complex samples.

Multi-branched metal nanomaterials can exhibit precisely controllable plasmonic properties with the precise control of their sizes and morphologies. In this study, trepang-like gold nanocrystals (AuNCs) with tunable plasmonic properties were synthesized via DNA-directed self-assembly technology. The gold precursor was precisely controlled to be reduced and grow along the DNA skeleton of DNA-conjugated gold nanorods to form multi-branched trepang-like nanocrystals. It was investigated in detail and proven that several key factors greatly influenced the precise control of the morphology and plasmonic property of the proposed AuNCs during their synthesis, including the gold precursor, reducing agent, surfactant, loading amount of DNA and DNA structure. The relative finite-difference time-domain calculation results suggested that the change in the plasmonic resonance peak is consistent with the precise change in the size and morphology of the as-synthesized AuNCs. The trepang-like AuNCs exhibited broad absorption bands in the wavelength range of 700-1100 nm with a high photothermal conversion efficiency of 36.2%. Finally, the trepang-like AuNCs with good biocompatibility were applied in photothermal therapy and imaging analysis.

Synthesis of tunable DNA-directed trepang-like Au nanocrystals for imaging application

Magnetic Ti3C2Tx/Fe3O4/Ag substrate for rapid quantification of trace sulfonamides in aquatic products by surface enhanced Raman spectroscopy

Zhongning Yu

Papers

Rapid determination of trace nitrofurantoin in cosmetics by surface enhanced Raman spectroscopy using nanoarrayed hydroxyl polystyrene‐based substrate

Simultaneous and Accurate Quantification of Multiple Antibiotics in Aquatic Samples by Surface-Enhanced Raman Scattering Using a Ti3C2Tx/DNA/Ag Membrane Substrate.

Advanced sample preparation techniques for rapid surface-enhanced Raman spectroscopy analysis of complex samples.

Synthesis of tunable DNA-directed trepang-like Au nanocrystals for imaging application

Magnetic Ti3C2Tx/Fe3O4/Ag substrate for rapid quantification of trace sulfonamides in aquatic products by surface enhanced Raman spectroscopy