Z
Zhongqiu Liu
Researcher at Chinese Ministry of Education
Publications - 237
Citations - 5200
Zhongqiu Liu is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 34, co-authored 177 publications receiving 3596 citations. Previous affiliations of Zhongqiu Liu include Hong Kong Baptist University & Guangzhou University of Chinese Medicine.
Papers
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Journal ArticleDOI
Telomerase reverse transcriptase promotes epithelial–mesenchymal transition and stem cell-like traits in cancer cells
Zhongqiu Liu,Qi Li,Qi Li,K Li,L Chen,Wenjuan Li,M Hou,T Liu,J Yang,Charlotta Lindvall,Magnus Björkholm,Jihui Jia,Dawei Xu,Dawei Xu +13 more
TL;DR: Targeting hTERT may prevent cancer progression by inhibiting EMT and CSCs using gastric cancer as a model and demonstrates the in vivo stimulation of h TERT on cancer cell colonization.
Journal ArticleDOI
Natural polyphenol disposition via coupled metabolic pathways.
Zhongqiu Liu,Ming Hu +1 more
TL;DR: More research is needed to determine if the metabolites of polyphenols in plasma are active or reactive, which will help explain their mechanism of actions, and how these coupled processes enable a duo recycling scheme of enteric and enterohepatic recycling.
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Activation of Nrf2/HO-1 Pathway by Nardochinoid C Inhibits Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages.
Jin-Fang Luo,Xiu-Yu Shen,Chon-Kit Lio,Yi Dai,Chun-Song Cheng,Jian-Xin Liu,Yun-Da Yao,Yang Yu,Ying Xie,Pei Luo,Xin-Sheng Yao,Zhongqiu Liu,Hua Zhou,Hua Zhou +13 more
TL;DR: Findings suggested that Nardochinoid C could be a new Nrf2 activator for the treatment and prevention of diseases related to inflammation and oxidative stress.
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Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein.
Ling Ye,Tao Wang,Lan Tang,Wei Liu,Zhen Yang,Juan Zhou,Zhijie Zheng,Zheng Cai,Ming Hu,Ming Hu,Zhongqiu Liu +10 more
TL;DR: AP has poor oral bioavailability because of its rapid biotransformation and efflux by P-gp, and how intestinal disposition affects its bioavailability is determined.
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Developments of Combretastatin A-4 Derivatives as Anticancer Agents
TL;DR: In this review, the recent developments of novel CA-4 derivatives via the modifications on the A- and B-ring and the double bond as anticancer agents are discussed.