Z
Zhongwei Zhang
Researcher at Huazhong University of Science and Technology
Publications - 11
Citations - 77
Zhongwei Zhang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 7 publications receiving 38 citations.
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Journal ArticleDOI
Complications constitute a major risk factor for mortality in hepatitis B virus-related acute-on-chronic liver failure patients: a multi-national study from the Asia-Pacific region.
Tao Chen,Zhongyuan Yang,Ashok Choudhury,Mamun Al Mahtab,Jun Li,Yu Chen,Soek Siam Tan,Tao Han,Jinhua Hu,Saeed Hamid,Lee Guan Huei,Hasmik Ghazinian,Yuemin Nan,Yogesh Chawla,Man-Fung Yuen,Harshad Devarbhavi,Akash Shukla,Zaigham Abbas,Manoj Kumar Sahu,Abdülkadir Dökmeci,Laurentias A. Lesmana,Cosmas Rinaldi A Lesmana,Shaojie Xin,Zhongping Duan,Wei Guo,Ke Ma,Zhongwei Zhang,Qiuyu Cheng,Jidong Jia,B. C. Sharma,Shiv Kumar Sarin,Qin Ning +31 more
TL;DR: The Tongji prognostic predictor model score (TPPMs), which set the number of complications as one of the determinants, showed comparable or superior ability to the Chinese Group on the Study of Severe Hepatitis B–ACLF score (COSSH-ACLFs) and MELD–sodium score (MELD–Nas) in HBV– ACLF patients, especially in cirrhotic HBV-–AClF patients.
Journal ArticleDOI
Long non-coding RNA LINC00473 acts as a microRNA-29a-3p sponge to promote hepatocellular carcinoma development by activating Robo1-dependent PI3K/AKT/mTOR signaling pathway:
Qiqin Song,Hongyue Zhang,Jinan He,Hongyan Kong,Ran Tao,Yu Huang,Haijing Yu,Zhongwei Zhang,Zhiyong Huang,Lai Wei,Chenghai Liu,Likui Wang,Qin Ning,Jia-Quan Huang +13 more
TL;DR: LINC00473 might be involved in HCC progression by acting as a miR-29a-3p sponge to upregulate the expression of Robo1 that activates the PI3K/AKT/mTOR signaling pathway, which leads to enhanced cell proliferation, migration, invasion, tumor progression, and metastasis in H CC.
Journal ArticleDOI
Soluble fibrinogen-like protein 2 promotes the growth of hepatocellular carcinoma via attenuating dendritic cell-mediated cytotoxic T cell activity
Muyang Yang,Zhongwei Zhang,Jiajia Chen,Mengying Xu,Jiaquan Huang,Ming Wang,Weina Li,Xiaoyang Wan,Man-Fung Yuen,Xiaoping Luo,Dong Xi,Qin Ning +11 more
TL;DR: The data suggest that sF GL2 promotes hepatoma growth by attenuating DC activity and subsequent CD8+ T cell cytotoxicity, suggesting sFGL2 as a novel potential therapeutic target for HCC treatment.
Journal ArticleDOI
Plasma perfusion combined with plasma exchange in chronic hepatitis B-related acute-on-chronic liver failure patients
Zhongyuan Yang,Zhongwei Zhang,Qiuyu Cheng,Guang Chen,Weina Li,Ke Ma,Wei Guo,Xiaoping Luo,Tao Chen,Qin Ning +9 more
TL;DR: Evaluating the effectiveness of plasma perfusion combined with plasma exchange in patients with hepatitis B virus-related ACLF found PP’+ PE treatment significantly reversed organ failures and ameliorated the development of new organ failure and complications, thus reducing mortality risk of patients with HBV-ACLF.
Journal ArticleDOI
Establishment and validation of a prognostic model for hepatitis B virus‑related acute-on-chronic liver failure patients with bacterial infection.
Zhongwei Zhang,Zhongyuan Yang,Qiuyu Cheng,Xue Hu,Meiqi Liu,Yunhui Liu,Tingting Liu,Ke Ma,Meng Zhang,Xiaoping Luo,Tao Chen,Qin Ning +11 more
TL;DR: In this paper, the authors established and validated a nomogram for predicting 30-day mortality of hepatitis B virus-related ACLF (HBV-ACLF) patients with bacterial infection, which may facilitate optimal therapeutic strategies to improve the prognosis of these patients.