Z
Zhuo Ren Lu
Researcher at University of Maryland, Baltimore
Publications - 2
Citations - 163
Zhuo Ren Lu is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Ouabain & Pregnenolone. The author has an hindex of 2, co-authored 2 publications receiving 160 citations.
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Journal ArticleDOI
Observations on the Nature, Biosynthesis, Secretion and Significance of Endogenous Ouabain
John M. Hamlyn,Zhuo Ren Lu,Paolo Manunta,James H. Ludens,Keizo Kimura,Jui R. Shah,James Laredo,James P. Hamilton,Matthew J. Hamilton,Bruce P. Hamilton +9 more
TL;DR: It is suggested that at least one of the mammalian counterparts to the cardiac glycosides is a novel steroidal isomer of ouabain, which is secreted by the adrenal cortex, and augments cardiovascular function.
Journal ArticleDOI
11-hydroxylation in the biosynthesis of endogenous ouabain: multiple implications.
TL;DR: Accumulating evidence indicates that mammals use steroidal glycosides with ‘digitalis‐like’ activity and the existence of an additional ring in the hemiketals raises the possibility that their in vivo physiological targets and actions differ from the isolated form of EO.