Z
Zicheng Li
Researcher at Washington University in St. Louis
Publications - 5
Citations - 280
Zicheng Li is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Charge density & Nanomedicine. The author has an hindex of 4, co-authored 5 publications receiving 272 citations.
Papers
More filters
Journal ArticleDOI
Facile, efficient approach to accomplish tunable chemistries and variable biodistributions for shell cross-linked nanoparticles.
Guorong Sun,Aviv Hagooly,Jinqi Xu,Andreas M. Nyström,Zicheng Li,Raffaella Rossin,Dennis A. Moore,Karen L. Wooley,Michael J. Welch +8 more
TL;DR: The in vivo behavior of shell cross-linked knedel-like (SCK) nanoparticles is shown to be tunable via a straightforward and versatile process that advances SCKs as attractive nanoscale carriers in the field of nanomedics.
Journal ArticleDOI
Strategies for Optimized Radiolabeling of Nanoparticles for in vivo PET Imaging
Guorong Sun,Jinqi Xu,Aviv Hagooly,Raffaella Rossin,Zicheng Li,Dennis A. Moore,Craig J. Hawker,Michael J. Welch,Karen L. Wooley +8 more
TL;DR: This strategy involved a complete redesign of the nanoparticle system, utilizing macromolecular precursors that were preloaded with labeling sites and programmed for supramolecular assembly into discrete, functional nanoscale objects.
Journal ArticleDOI
Shell crosslinked nanoparticles carrying silver antimicrobials as therapeutics
Yali Li,Khadijah M. Hindi,Kristin M. Watts,Jane B. Taylor,Ke Zhang,Zicheng Li,David A. Hunstad,Carolyn L. Cannon,Wiley J. Youngs,Karen L. Wooley,Karen L. Wooley +10 more
TL;DR: Amphiphilic polymer nanoparticles loaded with silver cations or/and N-heterocyclic carbene-silver complexes were assessed as antimicrobial agents against Gram-negative pathogens Escherichia coli and Pseudomonas aeruginosa.
Journal ArticleDOI
Labeling of Polymer Nanostructures for Medical Imaging: Importance of Cross-Linking Extent, Spacer Length, and Charge Density
Jinqi Xu,Guorong Sun,Raffaella Rossin,Aviv Hagooly,Zicheng Li,Ken-ichi Fukukawa,Benjamin Weaver Messmore,Dennis A. Moore,Michael J. Welch,Craig J. Hawker,Karen L. Wooley +10 more
TL;DR: An intricate interplay between the chemical and physical properties of both the DOTA derivative and the SCK nanostructures was revealed, demonstrating the importance of structural control.
Journal Article
In vivo evaluation of 64Cu labeled PEGylated shell crosslinked nanoparticles (SCKs) as candidates for imaging and drug delivery
Yongjian Liu,Aviv Hagooly,Guorong Sun,Raffaella Rossin,Jinqi Xu,Andreas M. Nyström,Zicheng Li,Karen L. Wooley,Michael J. Welch +8 more
TL;DR: In this article, amphibilic diblock copolymers were conjugated with 2 DOTA and 0, 1, 2.4 or 5.5 PEG2000 chains per polymer and used to synthesize SCK1-4.