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Zsuzsanna Schelz
Researcher at University of Szeged
Publications - 27
Citations - 1089
Zsuzsanna Schelz is an academic researcher from University of Szeged. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 12, co-authored 20 publications receiving 966 citations.
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Journal ArticleDOI
Antimicrobial and antiplasmid activities of essential oils.
TL;DR: The interaction of peppermint oil and menthol with the antibiotics was studied on the same bacterial strain with the checkerboard method and a new mechanism of plasmid curing was established for one of the oil components.
Journal ArticleDOI
Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities.
Marta Martins,Sujata G. Dastidar,Séamus Fanning,Jette E. Kristiansen,Joseph Molnár,Jean-Marie Pagès,Zsuzsanna Schelz,Gabriella Spengler,Miguel Viveiros,Leonard Amaral +9 more
TL;DR: A review of agents that have been shown to be efflux pump inhibitors (EPIs) and which, if used as 'helper compounds' in combination with antibiotics to which the organism is initially resistant, may produce the required cure.
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Inhibition of quorum-sensing signals by essential oils
Mira Agnes Szabo,Gábor Varga,Judit Hohmann,Zsuzsanna Schelz,E. Szegedi,Leonard Amaral,József Molnár +6 more
TL;DR: The role of quorum sensing is well known in microbial pathogenicity and antibiotic resistance, and the inhibition of QS signals reduces the problem of resistance and virulence.
Journal ArticleDOI
The Mechanism of Plasmid Curing in Bacteria
Gabriella Spengler,Annamária Molnár,Zsuzsanna Schelz,Leonard Amaral,Derek Sharples,Joseph Molnár +5 more
TL;DR: Bacterial plasmids can be eliminated from bacterial species grown as pure or mixed bacterial cultures in the presence of sub-inhibitory concentrations of non-mutagenic heterocyclic compounds, and the inhibition of conjugational transfer of antibiotic resistance plasmid can be exploited to reduce the spread of antibiotic resistantplasmid in the ecosystem.
Journal ArticleDOI
In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis
Marta Martins,Zsuzsanna Schelz,Ana Martins,Joseph Molnár,György Hajós,Zsuzsanna Riedl,Miguel Viveiros,Ismail Yalcin,Esin Aki-Sener,Leonard Amaral +9 more
TL;DR: New derivatives of TZ were synthesised and their in vitro activity against a reference strain of M. tuberculosis was evaluated with the aid of the BACTEC 460 system and derivatives that presented significant activity were evaluated by ex vivo studies and were shown to enhance the killing of intracellular M.culosis.