Gazi University

About: Gazi University is a education organization based out in Ankara, Ankara, Turkey. It is known for research contribution in the topics: Population & Medicine. The organization has 10525 authors who have published 23719 publications receiving 424124 citations. The organization is also known as: Gazi Üniversitesi.

Curcumin, an Active Component of Turmeric (Curcuma longa), and Its Effects on Health

Abstract: Turmeric (Curcuma longa) is a type of herb belonging to ginger family, which is widely grown in southern and south western tropical Asia region. Turmeric, which has an importance place in the cuisines of Iran, Malesia, India, China, Polynesia, and Thailand, is often used as spice and has an effect on the nature, color, and taste of foods. Turmeric is also known to have been used for centuries in India and China for the medical treatments of illnesses such as dermatologic diseases, infection, stress, and depression. Turmeric's effects on health are generally centered upon an orange-yellow colored, lipophilic polyphenol substance called "curcumin," which is acquired from the rhizomes of the herb. Curcumin is known recently to have antioxidant, anti-inflammatory, anticancer effects and, thanks to these effects, to have an important role in prevention and treatment of various illnesses ranging notably from cancer to autoimmune, neurological, cardiovascular diseases, and diabetic. Furthermore, it is aimed to increase the biological activity and physiological effects of the curcumin on the body by synthesizing curcumin analogues. This article reviews the history, chemical and physical features, analogues, metabolites, mechanisms of its physiological activities, and effects on health of curcumin.

Weapon selection using the AHP and TOPSIS methods under fuzzy environment

Abstract: The weapon selection problem is a strategic issue and has a significant impact on the efficiency of defense systems. On the other hand, selecting the optimal weapon among many alternatives is a multi-criteria decision-making (MCDM) problem. This paper develops an evaluation model based on the analytic hierarchy process (AHP) and the technique for order performance by similarity to ideal solution (TOPSIS), to help the actors in defence industries for the selection of optimal weapon in a fuzzy environment where the vagueness and subjectivity are handled with linguistic values parameterized by triangular fuzzy numbers. The AHP is used to analyze the structure of the weapon selection problem and to determine weights of the criteria, and fuzzy TOPSIS method is used to obtain final ranking. A real world application is conducted to illustrate the utilization of the model for the weapon selection problem. The application could be interpreted as demonstrating the effectiveness and feasibility of the proposed model.

The Definition and Prevalence of Obesity and Metabolic Syndrome.

Abstract: Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total adiposity and truncal subcutaneous fat accumulation during adolescence are positively and independently associated with atherosclerosis at adult ages. Centrally accumulation of body fat is associated with insulin resistance, whereas distribution of body fat in a peripheral pattern is metabolically less important. Obesity is associated with a large decrease in life expectancy. The effect of extreme obesity on mortality is greater among younger than older adults. In this respect, obesity is also associated with increased risk of several cancer types. However, up to 30% of obese patients are metabolically healthy with insulin sensitivity similar to healthy normal weight individuals, lower visceral fat content, and lower intima media thickness of the carotid artery than the majority of metabolically “unhealthy” obese patients.