Novum

About: Novum is a based out in . It is known for research contribution in the topics: Estrogen receptor & Receptor. The organization has 659 authors who have published 578 publications receiving 27932 citations.

An observational study of assisted reproductive technology outcomes in new European Union member states: an overview of protocols used for ovarian stimulation.

Abstract: Background:The development of new fertility treatment options has facilitated individualized assisted reproductive technology (ART) protocols to improve outcomes. Manufacturing improvements to recombinant human follitropin alfa have allowed precise dosing based on mass (filled-by-mass; FbM) rather than bioactivity (filled-by-bioassay; FbIU). Continued monitoring and reporting of follitropin alfa treatment outcomes in routine clinical practice is essential.Objective:To provide an overview of the frequency of different controlled ovarian-stimulation protocols used in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles in new European Union member states, and to provide post-registration efficacy and safety data on follitropin alfa.Research design and methods:A 2-year, prospective, observational, multicentre, Phase IV study conducted at ART clinics in the Czech Republic, Estonia, Latvia, Lithuania, Poland, Slovakia and Slovenia. Women aged 18–47 years undergoing ovarian st...

The Relational Database Engine: An Efficient Validator of Temporal Properties on Event Traces

Abstract: Trace validation is the process of analyzing a log produced by a system to discover violations of some specification involving sequences of events. This paper presents a translation of Linear Temporal Logic properties into equivalent SQL expressions. Experimental results on four different scenarios show that off-the-shelf database engines outperform seven different trace validation techniques from past literature, sometimes by orders of magnitude.

Analiza awaryjności elementów krytycznych bloków 200 MW jako ważny element metodyki prognozowania trwałości

Abstract: [1] Raport ETD: 1230-gsp-178: F. Akther, J.P. Fernandes, C.A. Smith: Boiler Tube Failure Prevention and Management – ETD Ltd. 2012. [2} ASME CRDT 20-1: Risk-Based Inspection – Development of Guidelines: Vol. 1, General Document, 1991. Vol. 3, Fossil Fuel-Fired Electric Generating Station Applications, 1994. [3] ASME CRDT, Vol.41; Risk-based methods for equipment life management, 2003. [4] Zdankiewicz M.: Kontrola urządzeń energetycznych oparta o analizę ryzyka. Próba usystematyzowania zaleceń w oparciu o wytyczne ASME. Materiały konferencyjne „Diagnostyka i eksploatacja kotłów parowych w zmodernizowanych blokach energetycznych”. Sympozjum Informacyjno-Szkoleniowe Pro Novum. Wisła 1999. [5] API 580/581 – American Petroleum Institute US, Risk-based inspection-recommended practice (1996 – 2000). [6] VGB-M 130e – Recommendation for the introduction of risk-based maintenance. VGB PowerTech. 2004. [7] RIMAP CEN Workshop Document: Risk-based inspection and maintenance procedures for European Industry. Stuttgart/ Brussels, March 2007 (Dokument opracowany z udziałem Pro Novum). [8] Ablitt Ch., Cane B., Rogers M., Kirkland R.: Optimised Outage Planning of Fossil Boilers Using RiskwiseTM. Risk-Based Inspection Software. ETD RBM Seminar London. November 2006. [9] Trzeszczyński J., Murzynowski W., Stanek R.: Analiza ryzyka jako wsparcie utrzymania stanu technicznego urządzeń cieplno-mechanicznych elektrowni. Dozór Techniczny 2012, nr 4. [10] Sturm F.A.: Anlagenmanagement. VGB PowerTech. 2012. [11] Trzeszczyński J., Murzynowski W., Białek S.: Monitorowanie stanu technicznego urządzeń cieplno-mechanicznych bloków energetycznych przy wykorzystaniu platformy informatycznej LM System PRO+®. Dozór Techniczny 2011, nr 5. [12] Dobosiewicz J.: Badania diagnostyczne urządzeń cieplno-mechanicznych w energetyce. Część II. Kotły i rurociągi. Biuro Gamma. Warszawa 1996. [13] Gawron P., Klepacki F.: Trwałość wybranych elementów kotłów w warunkach współspalania biomasy. Energetyka 2012, nr 6. [14] PN/020.2900/2013 i PN/030.2910/2013: Wytyczne przedłużania czasu eksploatacji urządzeń cieplno-mechanicznych bloków 200 MW. Katowice, luty 2013. [15] Trzeszczyński J., Stanek R.: Analiza awaryjności elementów krytycznych bloków 200 MW jako ważny element metodyki prognozowania trwałości. Biuletyn Pro Novum 1/2013. Energetyka 2013, nr 6.

Dynamic fast-atom bombardment mass spectrometry of conjugated metabolites of benzo[a]pyrene

Abstract: The N-acetylcysteine, cysteine and gluathione conjugates of r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene as well as sulphuric and glucuronic acid conjugates of hydroxybenzo[a]pyrenes have been studied by fast-atom bombardment mass spectrometry (FABMS). Dynamic FABMS has been shown to be advantageous over conventional static FABMS giving more intense spectra with less material in both positive-and negative-ion modes. The spectra show quasmolecular ions and fragment ions indicative of the aglycome and/or the conjugating group.