Princess Anne Hospital

About: Princess Anne Hospital is a healthcare organization based out in Southampton, United Kingdom. It is known for research contribution in the topics: Population & Breast cancer. The organization has 423 authors who have published 709 publications receiving 44790 citations.

Smartphone-based lifestyle coaching modifies behaviours in women with subfertility or recurrent miscarriage: a randomized controlled trial

Abstract: Research question Is an online lifestyle coaching platform more effective at modifying periconceptional behaviours than standard advice offered by the UK National Health Service (NHS)? Design Women with subfertility or recurrent miscarriage were recruited to a two-centre randomized controlled trial. They were randomized to either the online lifestyle coaching platform Smarter Pregnancy (intervention) or periconceptional advice provided by NHS websites (control). Participants completed a lifestyle questionnaire at baseline, 6, 12, 18 and 24 weeks, and the results were used to tailor lifestyle coaching in the intervention group. At baseline, 12 and 24 weeks, composite risk scores (CRS) were calculated. A lower CRS corresponds to a healthier lifestyle. Results Of the 400 women recruited, 262 women were randomized (131 in each arm). At 12 weeks, a reduction in CRS (includes risk score for intake of folic acid, vegetables and fruits, smoking and alcohol) was observed in the intervention versus control arms. After correcting for baseline, the difference in the CRS between intervention and control was –0.47 (95% CI –0.97 to 0.02) at 12 weeks and –0.32 (95% CI –0.82 to 0.15) at 24 weeks. A statistically significant reduction in lifestyle risk scores was found in women with a body mass index (BMI) of 25 kg/m2 or above compared with those with a BMI below 25kg/m2. The odds of being pregnant at 24 weeks was increased in the intervention versus control (OR 2.83, 95% CI 0.35 to 57.76). Conclusions The Smarter Pregnancy coaching platform is more effective in delivering lifestyle advice and modulating behaviours to support women with a history of subfertility or recurrent miscarriage than standard online NHS advice.

Family history of breast cancer

Abstract: A woman comes to see you because she is approaching the age, 45, at which her sister developed breast cancer. She is worried about her risk and is keen to know if there are any preventive measures she can take.

Prenatal ultrasound findings in a fetus with otopalatodigital syndrome type II.

Abstract: We describe the prenatal diagnosis and post mortem findings, including fetal radiographs and bone histology, in a fetus with oto-palato-digital syndrome type II. The differential diagnosis and recurrence risks are discussed

Alternative site self blood glucose testing is preferred by women with gestational diabetes.

Abstract: Background: Women with gestational diabetes (GDM) need to assimilate information and management skills rapidly for their diabetes to prevent adverse pregnancy outcomes. Strict glycaemic control is necessary and is improved by regular self-monitoring of blood glucose. The Softsense® meter (MediSense Products, Witney, UK) is used on less sensitive body sites and combines lancing with testing. The study aim was to compare alternative site testing with traditional blood glucose monitoring in pregnancy. Subjects and Methods: An open-label randomised crossover study using Softsense and Optium ® (MediSense Products) meters was performed in 33 women with GDM and 19 women with pre-existing diabetes. Each meter was used for 2 weeks. Ease of use and learning, pain, convenience, and effect on daily activities were assessed by a visual analogue questionnaire. Results: Women with GDM found the Softsense less painful (P = 0.0001) and easier to use (P = 0.03). At the end of the study, 25 chose the Softsense meter in pref...