Institution
University of Colorado System
Education•Boulder, Colorado, United States•
About: University of Colorado System is a education organization based out in Boulder, Colorado, United States. It is known for research contribution in the topics: Computer science & Biology. The organization has 46 authors who have published 43 publications receiving 8788 citations.
Topics: Computer science, Biology, Medicine, Geology, Environmental science
Papers published on a yearly basis
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TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) as discussed by the authors was used to estimate the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015.
5,050 citations
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
4,804 citations
TL;DR: This report provides national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015.
522 citations
TL;DR: Despite the potential of emerging technologies to assist persons with cognitive disabilities, significant practical impediments remain to be overcome in commercialization, consumer abandonment, and in the design and development of useful products.
Abstract: Despite the potential of emerging technologies to assist persons with cognitive disabilities, significant practical impediments remain to be overcome in commercialization, consumer abandonment, and in the design and development of useful products.Barriers also exist in terms of the financial and organizational feasibility of specific envisioned products, and their limited potential to reach the consumer market. Innovative engineering approaches, effective needs analysis, user-centered design, and rapid evolutionary development are essential to ensure that technically feasible products meet the real needs of persons with cognitive disabilities.Efforts must be made by advocates, designers and manufacturers to promote better integration of future software and hardware systems so that forthcoming iterations of personal support technologies and assisted care systems technologies do not quickly become obsolete. They will need to operate seamlessly across multiple real-world environments in the home, school, com...
131 citations
TL;DR: In this article, a meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium was conducted, and the authors found that DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation.
Abstract: Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in the Pregnancy And Childhood Epigenetics Consortium, we find that DNA methylation in neonatal blood is associated with birthweight at 914 sites, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation (PBonferroni < 1.06 x 10-7). In additional analyses in 7,278 participants, <1.3% of birthweight-associated differential methylation is also observed in childhood and adolescence, but not adulthood. Birthweight-related CpGs overlap with some Bonferroni-significant CpGs that were previously reported to be related to maternal smoking (55/914, p = 6.12 x 10-74) and BMI in pregnancy (3/914, p = 1.13x10-3), but not with those related to folate levels in pregnancy. Whether the associations that we observe are causal or explained by confounding or fetal growth influencing DNA methylation (i.e. reverse causality) requires further research.
128 citations
Authors
Showing all 156 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Rubin M. Tuder | 107 | 372 | 37843 |
| Dana Dabelea | 78 | 421 | 26854 |
| D. Dunbar Ivy | 62 | 371 | 14345 |
| Robert P. Dellavalle | 57 | 421 | 66842 |
| Jack O. Burns | 55 | 365 | 9643 |
| Ivana V. Yang | 47 | 178 | 9710 |
| Clayton Lewis | 35 | 137 | 8602 |
| David Braddock | 25 | 69 | 3130 |
| Adel K. Younoszai | 22 | 63 | 2892 |
| Gregory C. Allen | 20 | 51 | 1729 |
| S. R. Johnson | 19 | 59 | 1941 |
| Krista W. Ranby | 19 | 39 | 919 |
| Katherine M. Sauer | 5 | 12 | 116 |
| Chinnaswamy Jagannath | 4 | 7 | 27 |
| Kewei Chen | 2 | 7 | 13 |