L
Leanne K. Küpers
Researcher at Wageningen University and Research Centre
Publications - 52
Citations - 3515
Leanne K. Küpers is an academic researcher from Wageningen University and Research Centre. The author has contributed to research in topics: Pregnancy & DNA methylation. The author has an hindex of 19, co-authored 46 publications receiving 2149 citations. Previous affiliations of Leanne K. Küpers include University Medical Center Groningen & Medical Research Council.
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Journal ArticleDOI
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
Bonnie R. Joubert,Janine F. Felix,Paul Yousefi,Kelly M. Bakulski,Allan C. Just,Carrie V. Breton,Sarah E. Reese,Christina A. Markunas,Christina A. Markunas,Rebecca C Richmond,Cheng-Jian Xu,Leanne K. Küpers,Sam S. Oh,Cathrine Hoyo,Olena Gruzieva,Cilla Söderhäll,Lucas A. Salas,Nour Baïz,Hongmei Zhang,Johanna Lepeule,Carlos Ruiz,Symen Ligthart,Tianyuan Wang,Jack A. Taylor,Liesbeth Duijts,Gemma C Sharp,Soesma A Jankipersadsing,Roy Miodini Nilsen,Ahmad Vaez,Ahmad Vaez,M. Daniele Fallin,Donglei Hu,Augusto A. Litonjua,Bernard F. Fuemmeler,Karen Huen,Juha Kere,Inger Kull,Monica Cheng Munthe-Kaas,Ulrike Gehring,Mariona Bustamante,Marie José Saurel-Coubizolles,Bilal M. Quraishi,Jie Ren,Jörg Tost,Juan R. González,Marjolein J. Peters,Siri E. Håberg,Zongli Xu,Joyce B. J. van Meurs,Tom R. Gaunt,Marjan Kerkhof,Eva Corpeleijn,Andrew P. Feinberg,Celeste Eng,Andrea A. Baccarelli,Sara E. Benjamin Neelon,Asa Bradman,Simon Kebede Merid,Anna Bergström,Zdenko Herceg,Hector Hernandez-Vargas,Bert Brunekreef,Mariona Pinart,Barbara Heude,Susan Ewart,Jin Yao,Nathanaël Lemonnier,Oscar H. Franco,Michael C. Wu,Albert Hofman,Albert Hofman,Wendy L. McArdle,Pieter van der Vlies,Fahimeh Falahi,Matthew W. Gillman,Lisa F. Barcellos,Ashok Kumar,Ashok Kumar,Ashok Kumar,Magnus Wickman,Magnus Wickman,Stefano Guerra,Marie-Aline Charles,John W. Holloway,Charles Auffray,Henning Tiemeier,George Davey Smith,Dirkje S. Postma,Marie-France Hivert,Brenda Eskenazi,Martine Vrijheid,Hasan Arshad,Josep M. Antó,Abbas Dehghan,Wilfried Karmaus,Isabella Annesi-Maesano,Jordi Sunyer,Akram Ghantous,Göran Pershagen,Nina Holland,Susan K. Murphy,Dawn L. DeMeo,Esteban G. Burchard,Christine Ladd-Acosta,Harold Snieder,Wenche Nystad,Gerard H. Koppelman,Caroline L Relton,Vincent W. V. Jaddoe,Allen J. Wilcox,Erik Melén,Erik Melén,Stephanie J. London +112 more
TL;DR: This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
Journal ArticleDOI
Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes
LifeCycle Project-Maternal Obesity,Ellis Voerman,Susana Santos,Susana Santos,Hazel Inskip,Pilar Amiano,Henrique Barros,Henrique Barros,Marie-Aline Charles,Marie-Aline Charles,Marie-Aline Charles,Leda Chatzi,George P. Chrousos,Eva Corpeleijn,Sarah Crozier,Myriam Doyon,Merete Eggesbø,Maria Pia Fantini,Sara Farchi,Francesco Forastiere,Vagelis Georgiu,Davide Gori,Wojciech Hanke,Irva Hertz-Picciotto,Irva Hertz-Picciotto,Barbara Heude,Barbara Heude,Marie-France Hivert,D. Hryhorczuk,Carmen Iñiguez,Anne M. Karvonen,Leanne K. Küpers,Hanna Lagström,Debbie A Lawlor,Irina Lehmann,Per Magnus,Renata Majewska,Johanna Mäkelä,Yannis Manios,Monique Mommers,Monique Mommers,Camilla Schmidt Morgen,George Moschonis,Ellen A. Nohr,Anne-Marie Nybo Andersen,Emily Oken,Agnieszka Pac,Eleni Papadopoulou,Eleni Papadopoulou,Juha Pekkanen,Costanza Pizzi,Kinga Polańska,Daniela Porta,Lorenzo Richiardi,Sheryl L. Rifas-Shiman,Nel Roeleveld,L. Ronfani,Ana Cristina Santos,M. Standl,Hein Stigum,Hein Stigum,Camilla Stoltenberg,E. Thiering,Carel Thijs,Maties Torrent,Tomas Trnovec,Marleen M.H.J. van Gelder,Lenie van Rossem,Andrea von Berg,Martine Vrijheid,Alet H. Wijga,Oleksandr Zvinchuk,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Keith M. Godfrey,Vincent W. V. Jaddoe,Romy Gaillard +76 more
TL;DR: In this meta-analysis of pooled individual participant data from 25 cohort studies, the risk for adverse maternal and infant outcomes varied by gestational weight gain and across the range of prepregnancy weights, however, the optimal gestations weight gain ranges had limited predictive value for the outcomes assessed.
Journal ArticleDOI
Preterm birth, infant weight gain, and childhood asthma risk : A meta-analysis of 147,000 European children
Agnes M.M. Sonnenschein-van der Voort,Lidia R. Arends,Johan C. de Jongste,Isabella Annesi-Maesano,S. Hasan Arshad,Henrique Barros,Mikel Basterrechea,Hans Bisgaard,Hans Bisgaard,Leda Chatzi,Eva Corpeleijn,Sofia Correia,Leone C A Craig,Graham Devereux,Cristian Dogaru,Miroslav Dostal,Karel Duchén,Merete Eggesbø,C. Kors van der Ent,Maria Pia Fantini,Francesco Forastiere,Urs Frey,Ulrike Gehring,Davide Gori,Anne C. van der Gugten,Wojciech Hanke,A. John Henderson,Barbara Heude,Carmen Iñiguez,Hazel Inskip,Thomas Keil,Cecily Kelleher,Manolis Kogevinas,Eskil Kreiner-Møller,Claudia E. Kuehni,Leanne K. Küpers,Kinga Lancz,Pernille Stemann Larsen,Susanne Lau,Johnny Ludvigsson,Monique Mommers,Anne-Marie Nybo Andersen,Lubica Palkovicova,Katharine C. Pike,Costanza Pizzi,Kinga Polańska,Daniela Porta,Lorenzo Richiardi,Graham Roberts,Anne Schmidt,Radim J. Sram,Jordi Sunyer,Carel Thijs,Maties Torrent,K. Viljoen,Alet H. Wijga,Martine Vrijheid,Vincent W. V. Jaddoe,Liesbeth Duijts +58 more
TL;DR: In this article, the authors performed an individual participant data meta-analysis for 147,252 children of 31 birth cohort studies to determine the associations of birth and infant growth characteristics with the risks of preschool wheezing (1-4 years) and school-age asthma (5-10 years).
Journal ArticleDOI
Impact of maternal body mass index and gestational weight gain on pregnancy complications: An individual participant data meta-analysis of European, North American and Australian cohorts
Susana Santos,Ellis Voerman,Pilar Amiano,Henrique Barros,Lawrence J. Beilin,Anna Bergström,Marie-Aline Charles,Leda Chatzi,Cécile Chevrier,George P. Chrousos,Eva Corpeleijn,Olga Costa,Nathalie Costet,Sarah Crozier,Graham Devereux,Myriam Doyon,Merete Eggesbø,Maria Pia Fantini,Sara Farchi,Francesco Forastiere,Vagelis Georgiu,Keith M. Godfrey,Davide Gori,Veit Grote,Wojciech Hanke,Irva Hertz-Picciotto,Barbara Heude,Marie-France Hivert,Daniel O. Hryhorczuk,Rae-Chi Huang,Hazel Inskip,Anne M. Karvonen,Louise C. Kenny,Berthold Koletzko,Leanne K. Küpers,Hanna Lagström,Irina Lehmann,Per Magnus,Renata Majewska,Johanna Mäkelä,Yannis Manios,Fionnuala M. McAuliffe,Sheila McDonald,John Mehegan,Erik Melén,Monique Mommers,Camilla Schmidt Morgen,George Moschonis,Deirdre M. Murray,Carol Ní Chaoimh,Ellen A. Nohr,Anne-Marie Nybo Andersen,Emily Oken,Adriëtte J J M Oostvogels,Agnieszka Pac,Eleni Papadopoulou,Juha Pekkanen,Costanza Pizzi,Kinga Polańska,Daniela Porta,Lorenzo Richiardi,Sheryl L. Rifas-Shiman,Nel Roeleveld,Luca Ronfani,Ana Cristina Santos,Marie Standl,Hein Stigum,Camilla Stoltenberg,Elisabeth Thiering,Carel Thijs,Maties Torrent,Suzanne Tough,Tomas Trnovec,Steve Turner,Marleen M.H.J. van Gelder,Lenie van Rossem,Andrea von Berg,Martine Vrijheid,Tanja G. M. Vrijkotte,Jane West,Alet H. Wijga,John Wright,Oleksandr Zvinchuk,Thorkild I. A. Sørensen,Debbie A Lawlor,Romy Gaillard,Vincent W. V. Jaddoe,Vincent W. V. Jaddoe +87 more
TL;DR: In this paper, the separate and combined associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact were assessed.
Journal ArticleDOI
Maternal body mass index, gestational weight gain and the risk of overweight and obesity across childhood: An individual participant data meta-analysis
Ellis Voerman,Susana Santos,Bernadeta Patro Golab,Bernadeta Patro Golab,Pilar Amiano,Ferran Ballester,Henrique Barros,Anna Bergström,Marie-Aline Charles,Marie-Aline Charles,Leda Chatzi,Leda Chatzi,Leda Chatzi,Cécile Chevrier,George P. Chrousos,Eva Corpeleijn,Nathalie Costet,Sarah Crozier,Graham Devereux,Merete Eggesbø,Sandra Ekström,Maria Pia Fantini,Sara Farchi,Francesco Forastiere,Vagelis Georgiu,Keith M. Godfrey,Keith M. Godfrey,Davide Gori,Veit Grote,Wojciech Hanke,Irva Hertz-Picciotto,Barbara Heude,Barbara Heude,Daniel O. Hryhorczuk,Rae-Chi Huang,Hazel Inskip,Hazel Inskip,Nina Iszatt,Anne M. Karvonen,Louise C. Kenny,Berthold Koletzko,Leanne K. Küpers,Hanna Lagström,Irina Lehmann,Per Magnus,Renata Majewska,Johanna Mäkelä,Yannis Manios,Fionnuala M. McAuliffe,Sheila McDonald,John Mehegan,Monique Mommers,Camilla Schmidt Morgen,Camilla Schmidt Morgen,Trevor A. Mori,George Moschonis,Deirdre M. Murray,Carol Ní Chaoimh,Ellen A. Nohr,Anne-Marie Nybo Andersen,Emily Oken,Adriette J. J. M. Oostvogels,Agnieszka Pac,Eleni Papadopoulou,Juha Pekkanen,Costanza Pizzi,Kinga Polańska,Daniela Porta,Lorenzo Richiardi,Sheryl L. Rifas-Shiman,Luca Ronfani,Ana Cristina Santos,Marie Standl,Camilla Stoltenberg,Elisabeth Thiering,Carel Thijs,Maties Torrent,Suzanne Tough,Tomas Trnovec,Steve Turner,Lenie van Rossem,Andrea von Berg,Martine Vrijheid,Tanja G. M. Vrijkotte,Jane West,Alet H. Wijga,John Wright,Oleksandr Zvinchuk,Thorkild I. A. Sørensen,Debbie A Lawlor,Romy Gaillard,Vincent W. V. Jaddoe +91 more
TL;DR: In this article, the authors conducted an individual participant data meta-analysis of data from 162,129 mothers and children from 37 pregnancy and birth cohort studies from Europe, North-America and Australia, using multilevel binary logistic regression models with a random intercept at cohort level adjusted for maternal socio-demographic and life style related characteristics.