Institution
University of Puerto Rico, Medical Sciences Campus
Education•San Juan, Puerto Rico, United States•
About: University of Puerto Rico, Medical Sciences Campus is a education organization based out in San Juan, Puerto Rico, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 1711 authors who have published 1496 publications receiving 27756 citations.
Papers published on a yearly basis
Papers
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TL;DR: The KNM-ER 407 calvaria represents a female robust australopithecine from East Africa, and water displacements of both endocasts yielded a mean cranial capacity of 506 cc, which is consistent with the cranial capacities of four other robust australspinecines.
12 citations
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TL;DR: It is suggested that the 5‐HT receptors are expressed on a morphologically distinct population of neurons while the cells with channels responsible for the fast inactivating proton‐induced current cannot be related to any distinct morphological cell type.
Abstract: Using the whole-cell patch-clamp technique, the effects of serotonin (5-HT) and increased acidity to produce membrane currents and to modify high threshold voltage-dependent calcium currents were studied in isolated dorsal root ganglion (DRG) cells of the frog maintained in short-term culture. DRG cells were classified by morphology into two types: (1) cells with a large number of dark rusty brown granules, and (2) cells devoid of these granules or with few scattered pale granules. Fast application of 5-HT (10-30 microM) induced a rapidly desensitizing inward current with a reversal potential at about 0 mV in 38 of 50 granule-containing neurons (76%) which was never observed (0/35) in "clear" neurons. This current was blocked by 10 nM (+)-tubocurarine. In addition, a small noninactivating outward current was also observed in most DRG neurons during 5-HT superfusion. A sudden decrease of pH from 7.4 to 6 or 5.8 induced a fast inactivating inward current of 100-300 pA in 74% of the "clear" neurons and only 24% of the granule-containing neurons. Small noninactivating membrane currents induced by lowering pH were observed in all neurons. Both 5-HT and increased extracellular H+ reduced the magnitude of high threshold calcium currents in all DRG neurons. It is suggested that the 5-HT receptors are expressed on a morphologically distinct population of neurons while the cells with channels responsible for the fast inactivating proton-induced current cannot be related to any distinct morphological cell type.
12 citations
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TL;DR: Given the spike times in a train and the observed overall response, this work uses least-squares minimization to construct the best estimated response and at the same time best estimates of the elementary response kernel and the other functions that characterize the spike-response transform.
12 citations
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TL;DR: Focus groups explored the experiences of rejection felt by members of such socially marginalized groups as intravenous drug users and sex workers at risk of becoming infected with HIV to discover why they engaged in maladaptive behaviors as a way of coping with felt stigma.
Abstract: Though many studies have conclusively linked felt stigma and HIV, few have focused on the experiences of rejection felt by members of such socially marginalized groups as intravenous drug users (IDU) and sex workers (SW). Using focus groups, our study explored these experiences in 34 individuals (17 male UDUs and 17 female SWs) at risk of becoming infected with HIV, the objective being to discover why they engaged in maladaptive behaviors as a way of coping with felt stigma. We used deductive and inductive analysis to codify the resulting data. Concepts associated with the word stigma, emotional reactions to felt stigma, and the impact of felt stigma on self-schema helped elucidate how the internalization of felt stigma can lead to negative affective states and self-destructive behaviors (e.g., drug use and syringe exchange). Results underline the importance of developing intervention models that reduce stigma as a means of HIV prevention in vulnerable populations.
11 citations
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TL;DR: The effectiveness of the keraSys patch graft is limited by the higher than expected early exposure rate found in this case series, and these results should be confirmed in other studies.
Abstract: Purpose. Tube-related exposure is a known complication of glaucoma drainage device (GDD) surgery. Our objective is to report the early (approximately 1 year) tube exposure rate of implants covered with a keraSys (IOP Inc., Costa Mesa, CA, USA) tissue reinforcement graft. Patients and Methods. A retrospective, noncomparative, consecutive case series of 42 eyes with GDD implantation with keraSys patch grafts was performed. Main outcome measurements included patch-related complications: patch exposure, tube exposure, wound dehiscence, and patch migration. Results. Forty-two eyes were followed for an average of 15.24 ± 10.44 months (range 1.0–32.3 months). Four (10%) eyes experienced patch-related complications: two with exposure 8 months postoperatively, one with exposure 13 months postoperatively, and one with exposure 4 weeks postoperatively. Conclusion. The effectiveness of the keraSys patch graft is limited by the higher than expected early exposure rate found in this case series. These results should be confirmed in other studies.
11 citations
Authors
Showing all 1734 results
Name | H-index | Papers | Citations |
---|---|---|---|
Martin C. Mihm | 109 | 611 | 48762 |
Helmut Kettenmann | 104 | 380 | 40211 |
Howard E. Gendelman | 101 | 567 | 39460 |
Glorisa Canino | 81 | 340 | 28559 |
John D. Meeker | 71 | 326 | 16422 |
Kathleen Puntillo | 61 | 176 | 16201 |
Luis M. Vilá | 61 | 247 | 12798 |
Gregory J. Quirk | 61 | 118 | 25677 |
Miles F. Wilkinson | 57 | 163 | 10617 |
Julie K. Andersen | 56 | 176 | 12638 |
Kaumudi Joshipura | 54 | 143 | 13944 |
Mark W. Miller | 54 | 257 | 12825 |
Anthony Auerbach | 48 | 130 | 6572 |
Cynthia Garcia Coll | 45 | 108 | 10664 |
Dean Falk | 41 | 133 | 6200 |