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Institution

University of Puerto Rico, Medical Sciences Campus

EducationSan Juan, Puerto Rico, United States
About: University of Puerto Rico, Medical Sciences Campus is a education organization based out in San Juan, Puerto Rico, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 1711 authors who have published 1496 publications receiving 27756 citations.


Papers
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Book ChapterDOI
01 Jan 2020
TL;DR: This chapter focuses on four topics to advance data mining to transform clinical and translational research findings into precision health: data mining strategies and techniques, warehousing in big data science, genomics in disease risk and prevention, and integration of multiple data sources to advance precision health.
Abstract: Clinical and translational research encompasses the transformation of scientific and clinical data obtained from multiple sources. For this data to become meaningful for prevention, early diagnosis, treatment, and prognosis of disease, it needs to be integrated, analyzed, and transformed. The continuous creation of new technology and methodology, together with the participation of multiple disciplines in the interpretation of data and the design of common language and criteria to define parameters, will facilitate translation. In this chapter, we focus on four topics to advance data mining to transform clinical and translational research findings into precision health. These are (1) data mining strategies and techniques; (2) warehousing in big data science; (3) genomics in disease risk and prevention, and (4) integration of multiple data sources to advance precision health.

5 citations

Journal ArticleDOI
TL;DR: Reduction of Sug1 expression is accompanied by decreased recruitment of CBP and CIITA to the MHC promoters and decreased histone H3 acetylation in these promoters, which suggest that Sug1 plays a critical role in transcription of MHC class I, and the M HC class II-like molecules, HLA-DM and Hla-DO.

5 citations

Journal ArticleDOI
TL;DR: Much evidence supports the proposal that a soluble protease from liver and muscle is a major agent for insulin destruction in those organs, and a considerable number of low molecular weight compounds examined for their ability to inhibit the destruction of the hormone by the enzyme from rat liver.

5 citations

Journal Article
TL;DR: The prevalence of dental sealants in the first permanent molars of 12-year olds living in Puerto Rico during 1997 is lower than that reported in the United States (18.5%).
Abstract: Objective: to estimate the prevalence of pit and fissure sealants on first permanent molars in twelve year olds living in Puerto Rico and to further evaluate dental sealant prevalence by 1) urban/rural and public/ private school status as well as 2) gender; Design: population-based, cross-sectional study; Setting: public and private schools encompassing the 11 health regions of Puerto Rico. Subjects: a probabilistic sample of 12-year old school attendees in Puerto Rico representing a population of approximately 70,000. Method: during April through December 1997, the first permanent molars of 1435 subjects were evaluated by visual and tactile methods for the presence of dental sealants. Results: the data collected revealed that 4.3% of 12 years olds presented at least one permanent first molar sealed. A statistically significant difference (p=0.01) between urban-public (2.5%), rural-public (3.39%) and urban-private (11.0%) schools was observed. The prevalence of sealants was higher in males (5.5%) than females (2.9%); (p= 0.02). Conclusions: the prevalence of dental sealants in the first permanent molars of 12-year olds living in Puerto Rico during 1997 (4.3%) is lower than that reported in the United States (18.5%). Sealant prevalence was higher in males and students attending (urban) private schools.

5 citations

Journal ArticleDOI
TL;DR: The possible functional role of R199 in tertiary structure, as well as in the binding of PRPP, is interpreted in the context of the reported three dimensional structure for the human HPRT.

5 citations


Authors

Showing all 1734 results

NameH-indexPapersCitations
Martin C. Mihm10961148762
Helmut Kettenmann10438040211
Howard E. Gendelman10156739460
Glorisa Canino8134028559
John D. Meeker7132616422
Kathleen Puntillo6117616201
Luis M. Vilá6124712798
Gregory J. Quirk6111825677
Miles F. Wilkinson5716310617
Julie K. Andersen5617612638
Kaumudi Joshipura5414313944
Mark W. Miller5425712825
Anthony Auerbach481306572
Cynthia Garcia Coll4510810664
Dean Falk411336200
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20243
20235
202238
2021168
2020144
201991