Institution
University of Puerto Rico, Medical Sciences Campus
Education•San Juan, Puerto Rico, United States•
About: University of Puerto Rico, Medical Sciences Campus is a education organization based out in San Juan, Puerto Rico, United States. It is known for research contribution in the topics: Population & Medicine. The organization has 1711 authors who have published 1496 publications receiving 27756 citations.
Papers published on a yearly basis
Papers
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01 Jan 2020TL;DR: This chapter focuses on four topics to advance data mining to transform clinical and translational research findings into precision health: data mining strategies and techniques, warehousing in big data science, genomics in disease risk and prevention, and integration of multiple data sources to advance precision health.
Abstract: Clinical and translational research encompasses the transformation of scientific and clinical data obtained from multiple sources. For this data to become meaningful for prevention, early diagnosis, treatment, and prognosis of disease, it needs to be integrated, analyzed, and transformed. The continuous creation of new technology and methodology, together with the participation of multiple disciplines in the interpretation of data and the design of common language and criteria to define parameters, will facilitate translation. In this chapter, we focus on four topics to advance data mining to transform clinical and translational research findings into precision health. These are (1) data mining strategies and techniques; (2) warehousing in big data science; (3) genomics in disease risk and prevention, and (4) integration of multiple data sources to advance precision health.
5 citations
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TL;DR: Reduction of Sug1 expression is accompanied by decreased recruitment of CBP and CIITA to the MHC promoters and decreased histone H3 acetylation in these promoters, which suggest that Sug1 plays a critical role in transcription of MHC class I, and the M HC class II-like molecules, HLA-DM and Hla-DO.
5 citations
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TL;DR: Much evidence supports the proposal that a soluble protease from liver and muscle is a major agent for insulin destruction in those organs, and a considerable number of low molecular weight compounds examined for their ability to inhibit the destruction of the hormone by the enzyme from rat liver.
5 citations
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TL;DR: The prevalence of dental sealants in the first permanent molars of 12-year olds living in Puerto Rico during 1997 is lower than that reported in the United States (18.5%).
Abstract: Objective: to estimate the prevalence of pit and fissure sealants on first permanent molars in twelve year olds living in Puerto Rico and to further evaluate dental sealant prevalence by 1) urban/rural and public/ private school status as well as 2) gender; Design: population-based, cross-sectional study; Setting: public and private schools encompassing the 11 health regions of Puerto Rico. Subjects: a probabilistic sample of 12-year old school attendees in Puerto Rico representing a population of approximately 70,000. Method: during April through December 1997, the first permanent molars of 1435 subjects were evaluated by visual and tactile methods for the presence of dental sealants. Results: the data collected revealed that 4.3% of 12 years olds presented at least one permanent first molar sealed. A statistically significant difference (p=0.01) between urban-public (2.5%), rural-public (3.39%) and urban-private (11.0%) schools was observed. The prevalence of sealants was higher in males (5.5%) than females (2.9%); (p= 0.02). Conclusions: the prevalence of dental sealants in the first permanent molars of 12-year olds living in Puerto Rico during 1997 (4.3%) is lower than that reported in the United States (18.5%). Sealant prevalence was higher in males and students attending (urban) private schools.
5 citations
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TL;DR: The possible functional role of R199 in tertiary structure, as well as in the binding of PRPP, is interpreted in the context of the reported three dimensional structure for the human HPRT.
5 citations
Authors
Showing all 1734 results
Name | H-index | Papers | Citations |
---|---|---|---|
Martin C. Mihm | 109 | 611 | 48762 |
Helmut Kettenmann | 104 | 380 | 40211 |
Howard E. Gendelman | 101 | 567 | 39460 |
Glorisa Canino | 81 | 340 | 28559 |
John D. Meeker | 71 | 326 | 16422 |
Kathleen Puntillo | 61 | 176 | 16201 |
Luis M. Vilá | 61 | 247 | 12798 |
Gregory J. Quirk | 61 | 118 | 25677 |
Miles F. Wilkinson | 57 | 163 | 10617 |
Julie K. Andersen | 56 | 176 | 12638 |
Kaumudi Joshipura | 54 | 143 | 13944 |
Mark W. Miller | 54 | 257 | 12825 |
Anthony Auerbach | 48 | 130 | 6572 |
Cynthia Garcia Coll | 45 | 108 | 10664 |
Dean Falk | 41 | 133 | 6200 |