Showing papers in "Arab Journal of Gastroenterology in 2018"

TL;DR: This review summarizes the relationships between oxidative stress and different liver pathogenesis induced by drugs and xenobiotics, focusing upon different chronic liver injury induced by alcohol, antitubercular drugs and hyperactivity of antiretroviral drugs in HIV patients, viral hepatitis infection induced oxidative stress.

TL;DR: The various factors involved in pathophysiology of IBS, especially gut microbiota are discussed; probiotics, prebiotics and antibiotics have shown some promising results in managing IBS symptoms via modulating the interaction between the above.

TL;DR: The addition of DM to the currently used scores (Child-Pugh and MELD scores) may enhance the sensitivity and the specificity for prediction of morbidity and mortality rates in cirrhotic patients.

TL;DR: The results suggest that MMP-9 might be involved in the pathogenesis of H. pylori and PUD could be associated with cag PAI-dependent M MP-9 upregulation.

TL;DR: A BUN/Cr ratio of >30 was found to be an independent risk factor for mortality and may be useful for pre-endoscopic assessment and development of future risk scoring systems might warrant consideration of including BUN-Cr ratio as a parameter for estimating risk.

TL;DR: Testing for hepatitis C virus -RNA in peripheral blood mononuclear cells is more reliable in identifying patients with an OCI when a liver biopsy is not available than isolation of patients on dialysis machines depending on the results of hepatitis serological markers.

TL;DR: Survival following HCV-HCC in Egyptian patients undergoing HCC management in a specialised clinic setting is poor, although similar to high income country settings.

TL;DR: EUS-elastography and the SR could be excellent prognostic indices in differentiating benign from malignant lymph nodes if combined with other US features.

TL;DR: Preclinical and clinical efforts towards the application of dendritic cell (DC)-based immunotherapy for pancreatic cancer are reviewed.

TL;DR: The findings confirm the suggestion that IL-23 level measurement may be of value as a non-invasive test in the diagnosis and disease severity assessment in patients with UC.

TL;DR: Rifaximin and metronidazole are equally effective in management of acute episode of overt HE, therefore, re-auditing of treatment protocols of HE are warranted especially in limited resource settings.

TL;DR: The prevalence of OBI is lower than expected amongst CHC patients in Turkey and it may not be necessary to apply routine screening to IFN non-responders for OBI infection before DAA therapy, however, there is a need for multicentre studies with larger patient series.

TL;DR: A patient with a giant Brunner's gland hamartoma in the duodenum who was safely treated by endoscopic mucosal resection (EMR) is described, who was having gastrointestinal bleeding originating from this lesion.

TL;DR: This case report confirms that CD diagnosis in CVID patients is difficult; the combination of anti-endomysial antibodies (EmA-IgA), anti-tissue transglutaminase antibodies (tTG-IGAb) antibodies and total IgA is obligatory in basic diagnostic of CD but in C VID are negative.

TL;DR: Acute lower gastrointestinal bleeding is common among elderly patients and the commonest cause is diverticular disease, and the correlation between positive colonoscopy finding and diabetes and the use of nonsteroidal anti-inflammatory drugs were statistically significant.

TL;DR: A rare case of globular amyloidosis involving the large bowel, which to the best of the knowledge is the second reported in the world literature, is reported.

TL;DR: "Post-cut" is a feasible, effective, and safe endoscopic technique when impaction of a biliary stone with an entrapped extraction basket develops, and is coined the term "post- cut" referring to this technique.

TL;DR: In this article, an anonymous testing for hepatitis C virus (HCV) was offered to 150 residents and physicians from different departments (surgery, otolaryngology, gastroenterology, anaesthesiology and laboratory) in Damascus Hospital using fourth-generation enzyme-linked immunosorbent assay (ELISA).

TL;DR: EGFR expression by immunohistochemistry in CRC is variably correlated with clinicopathological parameters and its assessment by this method has still not proved its predictive value.

TL;DR: Downregulation of Nir1 and up regulation of Nir2 and FHIT genes due to the overexpression of TGIF2LX suggests that the gene plays an important role as a suppressor in colorectal adenocarcinoma.

TL;DR: Vasculitis may contribute to the development of neuropsychiatric involvement in HCV patients and be associated with systemic vasculitis on SPECT, which is associated with lower total WMS scores and higher anxiety and depression scores.

TL;DR: Sustained virologic response was documented and the skin lesions are almost disappeared without any topical or systemic treatment.

TL;DR: A case of PD ascariasis diagnosed on endoscopic ultrasound is presented and it is shown that worm extraction is associated with rapid relief of symptoms.

TL;DR: A personalised choice of the best treatment for PPI-resistant GORD should be based on the results of an upper endoscopy and pH/MII monitoring, and the execution of trials for testing double doses of PPIs against alternative medicaments is encouraged.

TL;DR: DBE is an excellent endoscopic procedure that has a relatively high diagnostic and therapeutic yield and exhibits a high safety profile with a low complication rate when performed by an experienced endoscopist.

TL;DR: This study is a pioneer clinical study on two functional SNPs in PKR promoter region and the TT genotype in rs12992188 polymorphism shows association with response to treatment, and patients with TT genotypes were more likely to achieve SVR.

TL;DR: The association between HER2 expression and PI3KCA alteration in gastric adenocarcinoma is most probably necessary to identify trastuzumab responders and thus may be considered as good candidates for multi-drug targeted therapy.

TL;DR: The ciprofloxacin group gave better results than the other 2 groups regarding total and differential leucocytic count and C-reactive protein level and no significant difference was found between oral and intravenous routes among the 3 groups.

TL;DR: Tissue acquisition in cases of splenic malignant lymphoma by using a conventional needle with multiple strokes and suction may result in indeterminate ROSE, whereas EUS-FNB by using the Franseen needle with a minimal number of strokes with suction demonstrates qualified specimens for the ROSE as well as histological examination.

TL;DR: Serum and hepatic Cu concentrations were markedly elevated in patients with cholestasis and positively correlated with each other and with S. ceruloplasmin, indicating that Cu level can predict hepaticCu concentration.