Showing papers in "Contraception in 1972"

TL;DR: It is concluded that ovarian function is not depressed to post-menopausal levels in women receiving oral steroidal contraceptive agents.

TL;DR: By means of neutron activation analysis, the concentrations of copper, zinc, manganese, sodium and potassium were estimated in the endometrium and cervical mucus in sixteen women using the Cu-T device and the daily release of copper from the device is almost constant during one year.

TL;DR: Immunoelectrophoresis demonstrated that many serum constituents are present in Human Tubal Fluid, and γ G is the major immunoglobulin constituent present in HTF.

TL;DR: A group of men who had vasectomy for contraceptive purposes were available as a model to study the in situ autoantigenicity of human spermatozoa, and apparently, two patterns of time-response may occur.

TL;DR: The photometric alkaline hematin procedure indicated a sensitivity to less than .1 ml of blood, within-batch precision of 5% or less (2 C.V.), and an accuracy of measuring human menstrual blood from most sanitary devices generally within plus or minus 5%.

TL;DR: Copper wire exhibited a distinct inhibition of the motility and penetration of human spermatozoa in human cervical mucus, while palladium and stainless steel wires did not.

TL;DR: The possibility of using testosterone as an antifertility agent in human males is suggested and quantity of semen did not show any variations during the period of testosterone administration and recovery.

TL;DR: The presence of metals, especially copper, in the cervical mucus inhibits and stops sperm penetration and consideration of these findings as the basis for a locally acting contraceptive method is suggested.

TL;DR: 41 preparations (jellies, creams, foams, etc.) were tested each in several dilutions with physiological saline for effect on inhibition of growth of C. albicans and T. vaginalis, finding that some of these preparations might reduce the female's risk of contracting either infection during intercourse.

TL;DR: Research is needed on the adverse side effects of vasectomy such as the abnormal uric acid found by Dr. Winer and possible immunological problems and vasectomies would have to be performed in clinics which kept adequate records.

TL;DR: The advantages of the TCu 200 over Loop D which have been suggested by previous preliminary clinical comparisons continue to be apparent, although the differences are becoming somewhat less marked as the magnitude of the data increases.

TL;DR: From 1968-1971 at the Birth Control Clinic of Ain Shams University Cairo Egypt 171 women (age 18-40 years) of proven fertility were given 200 mg of the long-acting injectable norethisterone enanthate as a contraceptive on the second to fourth day of the menstrual cycle and every 84 days thereafter.

TL;DR: Since the enzymes examined are involved with the implantation of the ovum, their alterations may be the mode of action of the Cu-T.

TL;DR: The data suggest that fertility control, which is the primary purpose of using oral contraceptive medication, can be accomplished with formulations containing up to 60 percent less estrogen than is present in currently available products.

TL;DR: The contraceptive effectiveness of megestrol acetate (M.A.) implants was evaluated in 126 parous young women and three pregnancies occurred in patients observed for up to 15 months for over 1,440 cycles.

TL;DR: Data suggest that a relative vitamin B 6 deficiency in oral contraceptive users, perhaps acting through an increase in the resulting circulating xanthurenic acid levels, is related in part to the observed carbohydrate metabolism deterioration.

TL;DR: 186 women ranging in age from 18-40 years were selected from the Los angeles Planned Parenthood Clinic and used the Cu-7 intrauterine device for 1693 woman-months, finding the device was effective and well tolerated.

TL;DR: The increase in the copper concentration of the uterine fluid might be the cause of the Cu-T antifertility effect due to a spermatotoxic and/or blastotoxic effect, as may the enzymic changes and increase of white blood cells.

TL;DR: Estrogen administration during the luteal phase of the menstrual cycle resulted in rapid decline of progesterone levels in the peripheral plasma of 13 out of 16 cycles in macaque monkeys, and in most instances, values returned to normal whether or not estrogen was continued.

TL;DR: The morphology of the human endometrium was investigated before, during and after the use of the Cu-T device as mentioned in this paper, where biopsies were obtained at regular intervals during a period of 12 months.

TL;DR: The authors noted that the increase in circulating vitamin-A, about 900 mcg, is far lower than the supplement of 3000 mcg daily widely prescribed for pregnant women, and not likely to be teratogenic in case of pregnancy.

TL;DR: Fertility control is indicated by either using the LH-releasing factor to precisely date the time of ovulation, providing accuracy to the rhythm method, or through development of a synthetic LRF antagonist to prevent fertility by inhibiting the LH/FSH factor.

TL;DR: Further studies are required before the synthetic decapeptide p-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-gly-NH2 can be used for therapeutic and contraceptive purposes.

TL;DR: Low density polyethylene, homogeneously loaded with 2% progesterone and 12% barium sulfate, was tested as a matrix from which to fabricate biochemically active intrauterine devices and showed that progestersone release rates, while initially high, attained a relatively constant value of 14 μg/day/cm 2 after the sixth day.

TL;DR: It is suggested that the Copper-T device interferes with certain phases of the glycogen metabolism of the endometrium as well as with cyclic variation in activity in normally menstruating women.

TL;DR: Depo-Provera was administered in a dose of 300 mg medroxyprogesterone acetate every six months as an injectable contraceptive agent by seven investigators to 991 patients for a total of 21,470 woman-months experience over a four year period.

TL;DR: The results suggest that testosterone may have some part in the control of serum FSH as well as LH levels in normal males.

TL;DR: Ovaries from steroid treated patients appeared to have a large number of atretic follicles with cystic dilatations, and an increase in ovarian connective tissue occurred in half of the cases using combined preparations, one third of those using sequential, and almost all of the those using depot progestin.

TL;DR: Mouse blastocysts were incubated in different concentrations of CuCl 2 in Brinster's medium with serum and a concentration of 0.1 mmol/l, that is nearly the same concentration as in cervical secretion from women with a copper-IUD, influenced all the three parameters.

TL;DR: The NET treatment does appear contraceptively effective if administered before implantation, and further research with a different experimental design is indicated.