J
John V. Frangioni
Researcher at Beth Israel Deaconess Medical Center
Publications - 280
Citations - 32600
John V. Frangioni is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Sentinel lymph node & Indocyanine green. The author has an hindex of 75, co-authored 278 publications receiving 29848 citations. Previous affiliations of John V. Frangioni include Massachusetts Institute of Technology & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Renal clearance of quantum dots.
Hak Soo Choi,Wenhao Liu,Preeti Misra,Eiichi Tanaka,John P. Zimmer,Binil Itty Ipe,Moungi G. Bawendi,John V. Frangioni,John V. Frangioni +8 more
TL;DR: This study has precisely defined the requirements for renal filtration and urinary excretion of inorganic, metal-containing nanoparticles and provides a foundation for the design and development of biologically targeted nanoparticles for biomedical applications.
Journal ArticleDOI
In vivo near-infrared fluorescence imaging
TL;DR: This review focuses on those parameters that affect image signal and background during in vivo imaging with near-infrared light and exogenous contrast agents.
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Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping
Sungjee Kim,Yong Taik Lim,Yong Taik Lim,Edward G. Soltesz,Alec M. De Grand,Jaihyoung Lee,Akira Nakayama,J. Anthony Parker,Tomislav Mihaljevic,Rita G. Laurence,Delphine M. Dor,Lawrence H. Cohn,Moungi G. Bawendi,John V. Frangioni +13 more
TL;DR: It is demonstrated that the fluorescence emission of type II quantum dots can be tuned into the near infrared while preserving absorption cross-section, and that a polydentate phosphine coating renders them soluble, disperse and stable in serum.
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Image-guided cancer surgery using near-infrared fluorescence.
Alexander L. Vahrmeijer,Merlijn Hutteman,Joost R. van der Vorst,Cornelis J. H. Van De Velde,John V. Frangioni +4 more
TL;DR: The concept of NIR fluorescence imaging for cancer surgery is introduced, the clinical trial literature to date is examined, and the key issues pertaining to imaging system and contrast agent optimization are outlined.
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Solubilization and Purification of Enzymatically Active Glutathione S-Transferase (pGEX) Fusion Proteins
TL;DR: This work has adapted a protocol, previously used to solubilize actin, for the purification of otherwise insoluble GST fusion proteins, and demonstrates that saturation of glutathione agarose is dependent on fusion protein molecular weight.