scispace - formally typeset
Search or ask a question

Showing papers in "Experimental Neurology in 1964"


Journal ArticleDOI
TL;DR: An intracellular analysis from the involved elements was carried out during the development and course of the organized rhythmical electrographic seizures simultaneously monitored with surface electrodes, finding that some neurons appear to be activated only in the later phases of the seizure.

767 citations


Journal ArticleDOI
TL;DR: Electric stimulation of single ampullary nerves in alert cats and monkeys produced rapid stereotyped head movements that demonstrated the specific nature of the reflex head and postural movements produced by the semicircular canals in these animals.

220 citations


Journal ArticleDOI
TL;DR: The neurobehavioral analysis indicated that the anatomical system controlling the expression of emotional or affective behavior also participates in the control of goal-directed motivated behavior.

194 citations


Journal ArticleDOI
TL;DR: Eye movements from single anterior canal nerve stimulation which appeared disconjugate from the front of the animal were associated when viewed from the plane of rotation of the head, and data show that the degree of ocular dissociation and the direction of the eye movements can be mathematically approximated.

157 citations


Journal ArticleDOI
TL;DR: It is concluded that there is considerable cholinesterase activity not associated with sole plates and that denervation produces a very rapid decrease in cholinerase activity.

153 citations


Journal ArticleDOI
TL;DR: In contrast to normals and brain-damaged controls, cats with bilateral hippocampal or orbitofrontal lesions are severely impaired in their ability to reverse tactile discrimination problems.

137 citations


Journal ArticleDOI
TL;DR: The production, by stimulation of the mesencephalic tegmentum, of a negative slow wave occluding a lumbosacral dorsal root potential suggests a presynaptic mechanism for inhibition of activity in the spinocervical tract.

122 citations


Journal ArticleDOI
TL;DR: Tonus of most head and neck muscles studied decreased with the onset of EEG stage I-rapid eye movement sleep, yet trunk and limb muscles exhibited stable levels of tonic activity throughout the night with no change of level associated with rapid eye movement periods.

107 citations


Journal ArticleDOI
TL;DR: It is concluded that the septal syndrome is not a necessary condition for the improved learning of a conditioned avoidance response in Long-Evans hooded rats and a training procedure using a fixed intertrial interval and a guillotine door separating the two compartments of the avoidance apparatus.

100 citations


Journal ArticleDOI
TL;DR: This survey was undertaken to determine whether the squirrel monkey might serve as an appropriate and economical substitute for macaques or baboons in electrophysiological investigations of the primate visual system, and to explore how the neuroanatomical differences between Saimiri and the commonly studied cat might be manifested in differing physiological characteristics.

98 citations


Journal ArticleDOI
TL;DR: Evoked responses were recorded from the auditory cortex of unanesthetized cats and the later components of the responses seemed to be more sensitive to changes in the state of the animal, while the early components seem to be abolished by local injury to the cortex.

Journal ArticleDOI
TL;DR: The tectospinal fibers appear to establish axosomatic and axodendritic synaptic contacts with large as well as small neurons within their laminae of termination within their spinal gray matter.

Journal ArticleDOI
TL;DR: Examination of nerve fiber supply to various cortical areas of several vertebrate animals has been examined by means of the electron microscope, and evidence here presented indicates that similar-size components have been successively acquired during the phylogenetic development of the mammalian cortex.

Journal ArticleDOI
TL;DR: Since the normal geniculate neuron increased in cross-sectional area about 50–60% from birth to 15 weeks of age, this suggests that visual deprivation arrests normal growth of the neuron without significantly altering its metabolic activity.

Journal ArticleDOI
TL;DR: It is concluded that spinal cord regeneration in the goldfish is age dependent; however, regeneration was sufficient in all age groups studied to result in complete restitution of function.

Journal ArticleDOI
TL;DR: Newborn rhesus monkeys have “physiological jaundice,” reticulocytosis, lower level of glucuronyl transferase in the liver and slower bilirubin clearnace time than adults, and probably asphyxia is only one of several agents causing cellular injury to bring about the picture of kernicterus in the presence of excess bilirubs in the blood.

Journal ArticleDOI
TL;DR: Microelectrode “sounding” confirmed the presence of two bilateral aggregates of bulbar respiratory neurons in and along the branchial motor nuclei of the ninth and tenth cranial nerves and favors the existence of a compact rather than a diffuse respiratory center.

Journal ArticleDOI
TL;DR: It is concluded that the non-PT, s neurons, which discharge before m neurons, do not drive the m neurons and are thought to be a functionally distinct population of neurons which inhabits the external granular layers of the cortex.

Journal ArticleDOI
TL;DR: Simultaneous records of evoked-potential patterns from various regions of the explants suggest maintenance of laminar organization of neural elements parallel to the original surface of the cerebral cortex, as well as in response to electric stimuli.

Journal ArticleDOI
TL;DR: The oscillatory prepyriform evoked potential model is presented in its simplest form as a linear time-invariant system based on essential characteristics of single neurons and their dominant interconnections and can be further developed to make its predicted output compatible with the patterns of gross electrical activity recorded from this cortex.

Journal ArticleDOI
TL;DR: The effect of acetylcholine has been studied on single units in the cerebral cortex of cats with the iontophoretic technique and this depressant action of ACh has several characteristic features and is distinct from that of current alone.

Journal ArticleDOI
TL;DR: It would appear that hippocampal damage interferes with activities involving alteration of a stabilized habit in cats with and without commissurotomies during tactile discrimination learning.

Journal ArticleDOI
TL;DR: A statistically significant difference was observed in the number of positive sera from Icelandic MS patients as compared with two groups of healthy Icelandic adults.

Journal ArticleDOI
TL;DR: The temporal firing patterns of units in the auditory cortex were studied as a function of stimulus parameters to show tonotopic organization of the cortex, where each column is maximally sensitive to a particular frequency.

Journal ArticleDOI
TL;DR: The specific impedance of cerebral cortex of rabbits anesthetized with urethane was measured during spreading cortical depression (SD) at frequencies from 5 to 50,000 cycle/sec, suggesting that the membrane change of neuroglia is similar to that of “anomalous rectification” of skeletal muscle.

Journal ArticleDOI
TL;DR: Modifications of evoked responses in subcortical stations along the auditory pathway are a passive reflection of middle ear muscle induced modifications of sound input.

Journal ArticleDOI
TL;DR: Pinched peripheral cutaneous nerves of the rat were permitted to degenerate and regenerate in situ for various periods of time before removal for observation in the electron microscope.

Journal ArticleDOI
TL;DR: It was concluded that the corticostriatal spreading depression transmission is realized through the claustrum and the lateral and basal nuclei of the amygdala, and this assumption was confirmed by making cuts and electrolytical lesions in the above-mentioned structures.

Journal ArticleDOI
TL;DR: The apparently paradoxical finding of a greater responsiveness of thalamic and cortical neurons when the animal is deeply asleep than during wakefulness is discussed.

Journal ArticleDOI
TL;DR: The Hebb-Williams maze, which consists of a battery of twelve different maze patterns, was used and the over-all score in this test was found to differentiate clearly between rats with hippocampal lesions and normal animals, confirming the previous findings that maze learning and passive avoidance learning are dependent on different brain structures.