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Showing papers in "Experimental Parasitology in 1960"



Journal ArticleDOI
TL;DR: This chapter discusses the advancement of research into Paragonimus and paragonimiasis in the taxonomic, immunodiagnostic, and chemotherapeutic fields.

105 citations


Journal ArticleDOI
TL;DR: It is concluded that the corpuscles serve tobuffer acids entering the body from the outside and, possibly, to buffer acids produced during aerobic and anaerobic fermentations.

68 citations


Journal ArticleDOI
TL;DR: The sera of some animals and of patients with toxoplasma antibodies in their blood reduced respiration of T. gondii, but this method of estimating antibodies is still in the experimental stage.

50 citations


Journal ArticleDOI
TL;DR: Evidence presented in this paper clearly suggests that the striking differences observed in the susceptibility of the two Brazilian strains of A. glabratus should be related to the snail and not to the trematode.

43 citations


Journal ArticleDOI
TL;DR: Adult Litomosoides carinii and adult Dirofilaria immitis have been maintained in vitro for 23 days and the females have produced microfilariae for 18 days, and infected larvae of D. immitis remained alive and healthy for 9 days in vitro.

42 citations


Journal ArticleDOI
TL;DR: Extracts of adult Trichuris muris were shown to hydrolyse a large number of substrates and the enzymes concerned have been partially characterized on the basis of pH optima, substrate specificities and response to activators and inhibitors.

41 citations



Journal ArticleDOI
Paul Actor1
TL;DR: The increase in parasite numbers resulting from protein depletion was found to be reversed by placing the deficient animals on an adequate diet, and the course of leishmaniasis was not altered in mice made thiamine deficient prior to or subsequent to infection.

38 citations


Journal ArticleDOI
TL;DR: In an extract of normal reticulocytes, the extent of glucose catabolism of free parasites was comparable with that which could be attributed to the parasite in the intact or lysed infected cell, in contrast oxygen consumption was much reduced.

38 citations


Journal ArticleDOI
TL;DR: The sensitivity of the subjects was greater to bites of P. irritans than to C. felis when measured either by immediate or delayed reactions, and younger age groups of both males and females were more sensitive than older age groups to the bites of fleas with respect to the delayed reaction.

Journal ArticleDOI
TL;DR: A microfluorimeter is described which can be used for the objective measurement of fluorescence of amebae stained with fluorescein-labeled antibody and some of the problems involved in obtaining relative and absolute measurements of fluorscein concentration are discussed.


Journal ArticleDOI
TL;DR: Albino rats maintained for 13 weeks on a riboflavin-deficient diet did not exhibit a significant increase in susceptibility to T. cruzi infection and the slight increase in severity of infection as evidenced by cardiac damage and parasitemia was attributed to inanition rather than to deficiency of the vitamin.

Journal ArticleDOI
TL;DR: Guinea pigs sensitized to one species of flea as a rule reacted to all flea species used in the experimental work reported here, which would seem to indicate the presence of a common antigenic factor present in P. irritans, P. simulans, and C. f.

Journal ArticleDOI
TL;DR: Guinea pigs sensitized to flea bites by previous exposure to Ctenocephalides felis felis showed both delayed and immediate types of reactivity, and the induction of sensitivity byflea bites was independent of the number of fleas biting.

Journal ArticleDOI
TL;DR: The estimation of the packed red-cell volume by the micro-hematocrit technique proved to be a convenient method of measuring anemia in chickens infected with E. tenella or E. necatrix and a marked retardation of growth occurred in birds in which only a mild anemia was detectable.

Journal ArticleDOI
TL;DR: The specificity of the reactions observed in Ouchterlony's double diffusion tests, in immunoelectrophoresis, and in intradermal reactions on humans with natural ascaris infections is considered.

Journal ArticleDOI
TL;DR: In this article, the distribution of nitrogen in five tissue fractions of M expansa, T actinioides, and C perplexa has been determined and β-alanine, β-aminoisobutyric acid, and γ-aminobutyrous acid were found to be common to all three species.

Journal ArticleDOI
TL;DR: Analysis of the extra-corporeal fluid of whole Echinococcus granulosus scolices at timed intervals during endogenous polysaccharide utilization showed the presence of glucose, fructose, ribulose, ribose, sedoheptulOSE, and glyceraldehyde, indicating that the pentose phosphate pathway occurs in E. granulosity.

Journal ArticleDOI
TL;DR: The evidence of development of all sexual stages in the haemocoels of the susceptible host and the failure to develop in the refractory species indicates that the factors governing susceptibility of A. albopictus and C. pipiens to P. fallax like those of previous host-parasite combinations are systemic and not restricted to tissues of the stomach wall.

Journal ArticleDOI
TL;DR: The mosquito phase of Plasmodium relictum has been cultivated in vitro as a series of steps from the stage of the gametocytes in the lumen of the stomach of the vector, Culex tarsalis until the appearance of sporozoites in the mature oocysts.

Journal ArticleDOI
TL;DR: Data on reproducibility of brightness readings indicate that when 50 amebae are measured per smear, differences in average brightness values may be considered statistically significant if they exceed 20–30% of the higher value.

Journal ArticleDOI
TL;DR: Evidence is presented for the presence of an opsonin in immune serum as an enhanced phagocytic effect over that produced by normal rat serum was observed, and some evidence is presented that there is a common antigen shared by T. lewisi and T. cruzi which is responsible for an enhancement of phagocytes activity of serum taken from rats which had been previously infected with T.cruzi.

Journal ArticleDOI
TL;DR: A simple chamber for the study of the sucking activity of Ancylostoma caninum in vitro is described, where the living worm is threaded through a thin rubber membrane, so that its head lies in blood tagged with Cr51, and its tail in 0.9% saline solution.

Journal ArticleDOI
TL;DR: It is suggested, that the positive thermotactic behavior of the infective larvae plays a vital part in the process of making contact with the rat host in nature.

Journal ArticleDOI
TL;DR: There were significant differences in the susceptibility of three pure strains of mice to infection with C. fasciolaris in all strains used and strain differences were accentuated in older animals.

Journal ArticleDOI
TL;DR: The effects of cortisone acetate administered to mice at different times relative to an initial infection with Schistosoma mansoni was studied in this paper, where the criterion of hormone influence upon the course of infection was the number of parasites recovered from treated and control mice six to eight weeks after infection.

Journal ArticleDOI
TL;DR: The present approach was the identification of the residues of hydrolysates of the secretions separated chromatographically, and it was concluded that the secretion contained polysaccharides in firm chemical union with proteins.

Journal ArticleDOI
TL;DR: Succinic dehydrogenase was the least active of the enzymes studied; lending an explanation to the production of succinic acid as the predominant end-product of aerobic carbohydrate metabolism in this species.