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Showing papers in "Journal of Laboratory and Clinical Medicine in 1957"


Journal ArticleDOI
TL;DR: A microprocedure for the direct determination of triglyceride concentrations in biologic specimens is presented and depends on the quantitative removal of phosphatides from the sample and the subsequent determination of esterified glycerol.

1,744 citations



Journal ArticleDOI
TL;DR: The fluorometric method is used to determine the amount of tyrosine in plasma from fasting patients with different disease states, as compared to the amountof the amino acid found in the plasma of normal fasting controls.

934 citations




Journal ArticleDOI
TL;DR: The ammonia found in freshly drawn human venous blood is believed to be preformed true ammonia, present as ammonium ions and not an artifact.

235 citations



Journal ArticleDOI
TL;DR: Variations in the oxygen saturation of multiple samples of mixed venous blood from the pulmonary artery from the same individual were consistent with the interpretation that the average maximal intra-individual variation in cardiac output, in these healthy subjects under conditions of supine rest, was ±17 per cent.

174 citations


Journal ArticleDOI
TL;DR: An anticoagulant with antithromboplastin effect was found in 2 patients who had hypergammaglobulinemia and hemorrhagic diathesis and whose sera gave false biologic reactions for syphilis.

166 citations





Journal ArticleDOI
TL;DR: The assay is based on the consumption of uridinediphospho-glucose in the presence of excess galactose-1-phosphate, and serves to diagnose cases of congenital Galactosemia.


Journal ArticleDOI
TL;DR: Experimental nephrosis has been produced in rats by the administration of 6-dimethylaminopurine-3-amino-d-ribose and the possible mechanism of action of the drug has been discussed.

Journal ArticleDOI
TL;DR: The data presented suggest that the deficient substance in plasma, aiding fibrin clot formation, did not appear to be platelets or any of the known plasma or serum coagulation factors, and is albumin or a substance related to albumin.

Journal ArticleDOI
TL;DR: It appears that sustained increases in blood steroid levels rather than short bursts of increased adrenal activity are required to elicit the phenomenon of increaed unit cell alkaline phosphatase activity, and it is not to be assumed at this time that the adrenal mechanism is the only one by which this phenomenon is elicited.



Journal ArticleDOI
TL;DR: A colorimetric microdiffusion technique for blood ammonia analysis has been described in this article, which combines modifications of the micro-diffusion unit of Seligson and the ninhydrin procedure of Moore and Stein.




Journal ArticleDOI
TL;DR: A solvent system applicable for assaying cholesterol digitonide in a liquid scintillation counter has been devised and a quick, convenient, and quantitative micromethod for isolating, measuring, and assaying radioactive free and ester cholesterol from plasma or tissue has been presented.


Journal ArticleDOI
TL;DR: A "drop" modification of the latex-fixation test for the serologic study of sera from patients ill with rheumatoid arthritis apparently achieves results in general agreement with those reported by other investigators who employed a macromethod.