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Showing papers in "Ophthalmology in 1984"


Journal ArticleDOI
TL;DR: The prevalence of macular edema and its relationship to a number of risk factors were examined in a population-based study in southern Wisconsin this paper, where the authors determined the presence of maculopathy from its presence on stereoscopic fundus photographs or from past history as recorded and documented in clinic records and photographs.

759 citations


Journal ArticleDOI
TL;DR: When assigning causes of impaired vision, diabetic retinopathy was responsible in part for 86% of eyes with visual acuity of 20/200 or worse in younger onset persons and for 33% in older onset persons.

584 citations


Journal ArticleDOI
TL;DR: The results show that the trabecular cellularity in NG specimens decreases most rapidly and in a nonlinear manner in the late fetal period and for the first few years of postnatal life, and this rapid decline in cellularity then slows down to proceed in a nearly linear manner for the remainder of the 98 years of life studied.

551 citations


Journal ArticleDOI
TL;DR: As judged by anatomical criteria and compared to normal adult foveas similarly processed, the human fovea reaches maturity between 15 and 45 months of age.

497 citations


Journal ArticleDOI
TL;DR: In this article, a review of 693 patients with bilateral retinoblastoma and 18 patients with unilateral/germinal GBM was carried out to find the incidence, time, course and pattern of second nonocular tumors in retinal cancer survivors, and the most common tumor was a sarcoma both in and out of the field of radiation.

386 citations


Journal ArticleDOI
TL;DR: It is indicated that CNM in degenerative myopia is usually self-limited, leaving an atrophic, nonexudative scar.

372 citations


Journal ArticleDOI
TL;DR: It seems that postoperative subconjunctival 5-FU increases the likelihood of achieving IOP control following filtering surgery in eyes with poor surgical prognoses; however, a randomized clinical trial is necessary to confirm this.

361 citations


Journal ArticleDOI
TL;DR: Twenty patients with acquired immunodeficiency syndrome (AIDS) died and the eyes were obtained for culture and histopathologic examination, and cytomegalovirus retinitis was a significant cause of visual loss.

297 citations


Journal ArticleDOI
TL;DR: It is the authors' impression that postoperative subconjunctival 5-FU increases the likelihood of achieving IOP control after filtering surgery in eyes with poor surgical prognoses; however, a randomized clinical trial is necessary to confirm this impression.

294 citations


Journal ArticleDOI
TL;DR: In this article, a non-randomized clinical trial comparing the ocular and systemic efficacy of cytotoxic immunosuppression with steroidal and nonsteroidal anti-inflammatory therapy in the care of 34 patients with rheumatoid arthritis who developed peripheral ulcerative keratitis and/or necrotizing scleritis.

285 citations


Journal ArticleDOI
TL;DR: Neither the ophthalmoscopic absence of optic atrophy nor the normal results of roentgenograms of the optic foramina were reliable predictors of tumors detected by CT scan, and the presence of optic glioma is not correlated to other ocular, skeletal, neurologic, or anamnestic risk factors.

Journal ArticleDOI
TL;DR: The classification scheme proposed appears useful for characterizing overall retinopathy severity of patients on the basis of gradings of fundus photographs, and its use in assessing progression ofretinopathy over a 6-year period in a group of insulin-taking patients is demonstrated.

Journal ArticleDOI
TL;DR: Twenty-five patients with central serious pigment epitheliopathy (CSP), also known as central serous chorioretinopathy, have been observed to have inferior hemispheric retinal pigment epithelial atrophic tracts, presumptive of antecedent retinal detachments.

Journal ArticleDOI
TL;DR: Children with pauciarticular juvenile chronic arthritis, especially when associated with antinuclear antibodies, are at particular risk of developing chronic uveitis and they should be screened at frequent intervals, even if asymptomatic.

Journal ArticleDOI
TL;DR: The macular blood flow response to an induced change in intraocular pressure (autoregulation) was studied using the blue field entopic phenomenon and results suggest an abnormal autoregulations of macular retinal blood flow in open-angle glaucoma.

Journal ArticleDOI
TL;DR: The ability of 5-fluorouracil to inhibit cicatrization at the filtering site in an experimental model is tested and Pharmacologic modulation of wound healing may decrease the risk of failure of filtering operations.

Journal ArticleDOI
TL;DR: The optic disc appearance in both the involved and normal fellow eye was studied in 51 patients with acute nonarteritic AION and the number of discs (both involved and fellow) without a physiologic cup was significantly greater than would be expected from normal population studies.

Journal ArticleDOI
TL;DR: The corneal endothelium is derived from the neural crest and may be considered according to a modification of this scheme to reflect its true embryologic origin.

Journal ArticleDOI
TL;DR: Trabeculectomies for secondary glaucomas were significantly more often successful in eyes that had not undergone previous surgery and the ability to identify patients at high risk for failure of trabecUlectomy may be of value in guiding the surgical management of glauca.

Journal ArticleDOI
TL;DR: In six eyes with proliferative retinopathy measured before and after panretinal photocoagulation, a significant increase in vascular response to O2 was observed following photocogulation (Wilcoxon signed rank test, P less than 0.05).

Journal ArticleDOI
TL;DR: Of 71 patients with only bilateral macular drusen, 8 eyes in 7 patients (9.9%) developed exudative maculopathy over an average follow-up of 4.3 years (14.5% cumulative risk) and severe visual loss occurred in 7 eyes of 6 patients for a 5-year cumulative risk of 12.7%.

Journal ArticleDOI
TL;DR: In combination with standard vitrectomy techniques, post-operative fluid gas exchange, and photocoagulation, periocular and subconjunctival 5-fluorouracil appears to improve the prognosis for longterm retinal reattachment following the development of proliferative vitreoretinopathy.

Journal ArticleDOI
TL;DR: The exenterated orbital contents obtained post mortem from a 47-year-old man who had an eight-month history of treated hyperthyroidism and a two- month history of visual complaints were examined histopathologically, immunohistochemically, and by electron microscopy to compatible with a compressive optic neuropathy mediated by the massively swollen extraocular muscles impinging upon the optic nerve at the orbital apex.

Journal ArticleDOI
TL;DR: Vitreous surgery was used to treat 130 consecutive cases with epiretinal membranes causing macular pucker, and vision improved at least two lines on the Snellen chart in 108 eyes.

Journal ArticleDOI
TL;DR: All four patients who had bilateral cataract surgery experienced either simultaneous flare-ups of both eyes or accelerated reactions after surgery on the second eye, which suggests a possible role of prior sensitization.

Journal ArticleDOI
TL;DR: It is speculated that loss of vascularization and intense inflammation may have an important effect on epithelial differentiation.

Journal ArticleDOI
TL;DR: A prospective short-term clinical study evaluated argon and Q-switched neodymium:YAG laser iridotomies in 40 eyes of 20 patients with primary chronic angle-closure glaucoma, finding a significant central corneal endothelial loss in argon laser treated eyes.

Journal ArticleDOI
TL;DR: Of 41 patients with adequate follow-up information, 10 lost at least two lines of visual acuity, usually due to tractional distortion of the fovea, and four had improvedVisual acuity following either amblyopia therapy or vitreous surgery for macular traction.

Journal ArticleDOI
TL;DR: In this article, the authors studied the sequential changes in the posterior capsule of the aphakic cat and monkey after extracapsular surgery using light microscopy, scanning electron microscopy and transmission electron microscope.

Journal ArticleDOI
TL;DR: Overall, 97% of eyes with NVG had a disease process that produced extensive retinal ischemia and preceded the onset of iris neovascularization, and patients withNVG, but without an obvious precipitating fundus condition, should be suspected of having severe carotid artery obstructive disease.