Showing papers in "Ophthalmology in 2009"

TL;DR: A 2-year phase III trial designated ANCHOR as discussed by the authors compared ranibizumab with verteporfin photodynamic therapy (PDT) in treating predominantly classic CNV.

TL;DR: The improved diagnostic power of macular GCC imaging is on par with, and complementary to, peripapillary NFL imaging and has potential for tracking glaucoma progression.

TL;DR: Compared with DSAEK, DMEK provided a significantly higher rate of 20/20 and 20/25 vision, with comparable endothelial cell loss, and Descemet's membrane endothelial keratoplasty restored physiologic pachymetry, but donor preparation and attachment currently are more challenging than with DSEK.

TL;DR: Corneal cross-linking seems to be effective in improving UCVA and BSCVA in eyes with progressive keratoconus by significantly reducing corneal APP, AK, and cornean and total wavefront aberrations at 1 year postoperatively.

TL;DR: Virreous fluid levels of VEGF, ICAM-1, IL-6, MCP- 1, and PEDF were related to retinal vascular permeability and the severity of DME and were significantly correlated with the retinal thickness at the central fovea.

TL;DR: The findings regarding initial surgery being beneficial for subjects with more advanced VF loss at presentation, but detrimental for patients with diabetes, are noteworthy and warrant independent confirmation.

TL;DR: In this article, the authors determined the age-specific prevalence of strabismus in white and African American children aged 6 through 71 months and of amblyopia in young children aged 30 through 31 months.

TL;DR: During a span of 6 months, ranibizumab injections by the current protocol had a significantly better visual outcome than focal/grid laser treatment in patients with DME.

TL;DR: Data show that relatively high 25-year cumulative rates of incidence of ME were related to glycemia and blood pressure, and the lower risk of incident ME in the last period of the study may reflect recent improvement in care.

TL;DR: In this 6-year follow-up study, the median untreated rate of progression corresponded to advancing from normal visual function to blindness in approximately 70 years, whereas on the basis of the mean rate, visual function would show the same deterioration in approximately 25 years.

TL;DR: Well-demarcated, hyperreflective foci were identified in the retina of patients with DME and it is suggested that the foci represent extravasated lipoproteins and/or proteins being a very early subclinical barrier breakdown sign in DME.

TL;DR: Intravitreal ranibizumab was safe and well tolerated in a large population of subjects with neovascular AMD and had a beneficial effect on VA, and future investigations will seek to establish optimal dosing regimens for persons with nevascular AMD.

TL;DR: This study showed that, in CRAO as well as BRAO, the prevalence of various cardiovascular diseases and smoking was significantly higher compared with the prevalenceof these conditions in the matched US population.

TL;DR: The Boston type I keratoprosthesis is an effective means of managing repeatCorneal graft failure and corneal limbal stem cell failure with or without Corneal opacification in patients with both unilateral and bilateral visual impairment.

TL;DR: Assessment of patient adherence and behaviors with topical once-daily therapy for glaucoma found nearly 45% of patients using an electronic monitoring device who knew they were being monitored and were provided free medication used their drops less than 75% of the time.

TL;DR: After anatomically successful RRD repair, FD-OCT is a valuable, noninvasive tool for evaluating foveal microstructural changes and may account for visual restoration in patients with preoperative macula-off RRDs.

TL;DR: A longitudinal study using SD OCT to examine and measure the neurosensory retina over drusen will resolve the timeline of degenerative changes relative to druse formation and suggest a degenerative process, with cell loss leading to decreased visual function.

TL;DR: In this article, the authors evaluated the outcome of treatment with methotrexate for non-infectious ocular inflammation and found that it is moderately effective for management of inflammatory activity and for achieving corticosteroid-sparing objectives, although many months may be required for therapeutic success.

TL;DR: Based on this review, worldwide, an average 95.4% of patients were satisfied with their outcome after LASIK surgery, and should be considered among the most successful elective procedures.

TL;DR: The prevalence of diabetic Retinopathy was 18% in an urban population with diabetes mellitus in India, and the duration of diabetes is the strongest predictor for diabetic retinopathy.

TL;DR: Ocular symptom score, lid margin abnormality score, meibo-score, meibum score, and SPK score were significantly higher in the obstructive MGD group than in the control group (P<0.0001) and the AUC values indicated that the ocular symptom scores had the highest diagnostic power as a single parameter.

TL;DR: In this article, the influence of contact lens wear on the meibomian glands using a newly developed meibographic technique was investigated, and it was found that approximately 30% to 50% of the wearers report dry eye symptoms.

TL;DR: In this article, the authors describe the disease characteristics and visual outcome of pediatric uveitis and describe the most significant visual impact of these characteristics and the most common types of complications.

TL;DR: After 3 years of participation in the trial, eyes randomized to atropine have less severe myopia than other eyes, and the absolute myopia progression after 3 years was significantly lower in the atropin group compared with placebo.

TL;DR: In cases of high myopia of -8 diopters or more, pIOLs may provide a better visual outcome than keratorefractive surgeries and better safety than refractive lens exchange and to have a lower risk of retinal detachment compared with refractive Lens Exchange.

TL;DR: Four major types of barriers to effective patient adherence to glaucoma medication adherence (medication regimen, patient factors, provider factors, and situational or environmental factors) have been identified and a systematic taxonomy of adherence barriers has been formulated.

TL;DR: Pupil responses that differ as a function of light intensity and wavelength support the hypothesis that selected stimulus conditions can produce pupil responses that reflect phototransduction primarily mediated by rods, cones, or melanopsin.

TL;DR: A high prevalence of diabetic retinopathy is reported among adults 30 years and older with diabetes in rural China and there is a pressing need for appropriate screening and management of diabetes and its complications in ruralChina.

TL;DR: To determine the agreement between peripapillary retinal nerve fiber layer (RNFL) thickness measurements from Stratus time domain optical coherence tomography (OCT) and Cirrus spectral domain OCT in normal subjects and subjects with glaucoma, two operators used the same instruments for all scans.