Showing papers in "Pathologie Biologie in 1999"

TL;DR: Findings support the concept that cardiovascular events are more related to the pulsatile stress of large artery stiffness during systole than the steady-state stress of small vessel resistance during diastole, and subjects with isolated systolic hypertension are at greater risk for cardiovascular events than those with combined syStolic/diastolic hypertension.

TL;DR: This new clinical approach links traditional sphygmography (originally introduced in France) with conventional cuff sp hygmomanometry, and is being evaluated in clinical and epidemiological studies.

TL;DR: Preliminary results from clinical phase I/II trials indicate that reversal of MDR via modulation of P-gp is possible and that coadministration of these MDR modulators with chemotherapeutic agents alters the plasma pharmacokinetics of chemotherAPEutic agents.

TL;DR: Age and blood pressure were found to be the most prominent predictors of arterial stiffness in normal as well as in disease populations.

TL;DR: A clear correlation between the percentage of S-phase PC and several prognosis features of MM has been found and multivariate analysis shows that the ratio between the number of clonal and normal residual PC is the best single parameter.

TL;DR: Results confirm the interest of IFN-tau as adjuvant therapy in HIV infection, and more particularly in HIV/HCV-infected patients.

TL;DR: Some of the biological, biochemical, and structural properties of angiogenin are discussed.

TL;DR: In this article, the authors present a critique of the points forts and faibles of two types of non-invasives methodologies, namely, indirect and direct, to evaluate the rigidite aortique.

TL;DR: To prevent stroke-related residual impairment and transfusion-related complications, BMT should be considered early in patients with Doppler or MRI evidence of silent stroke associated with cognitive function impairment, failure to respond to hydroxyurea therapy, or polyerythroalloimmunization.

TL;DR: In this article, the authors define a profusion of termes utilisee dans la litterature for decrire les proprietes elastiques des arteres peut etre source de confusion and rend difficile la comparaison des etudes et des equipes de chercheurs.

TL;DR: Signals that the anti-apoptopic protein Bcl-2 is a key element in multi drug resistance in myeloma suggests that therapies directed at lowering B cl-2 levels inMyeloma cells in vivo might chemosensitize the tumor cells and therefore might be applicable for therapeutic use.

TL;DR: The presence of nephrotic syndrome, renal insufficiency, congestive heart failure, orthostatic hypotension, or sensorimotor peripheral neuropathy, and an M-protein in the serum or urine suggest the possibility of primary amyloidosis.

TL;DR: This short review of the authors' own work presents two aspects of the studies on multiple myeloma (MM) in an animal model--the aging C57BL/KaLwRij mouse: the immunological/biological aspect of the development of monoclonal B-cell proliferative disorders, and the use of the mousemyeloma of the 5TMM lines for studies on the etiology/pathogenesis of MM and for developing new ways of treatment of this disease.

TL;DR: Cette modification du comportement d'autoguidage habituel s'explique probablement par l'association d'une evolution moleculaire vers une independance par rapport au stroma and d'un augmentation des possibilites d'extravasation.

TL;DR: It is concluded that, for a given ejection pattern (aortic flow), two arterial parameters, total arterial resistance andtotal arterial compliance are sufficient to accurately describe systolic and diastolic aortic pressure.

TL;DR: Although clinical outcomes were similar in the two groups, it is reasonable to assume that the longer time spent with a cefepime level above the MIC in the continuous infusion group was associated with a more stable bactericidal effect.

TL;DR: Evidence suggesting that calcium--and more importantly "calcification" of elastin fibres--is involved in the age-related increase in arterial stiffness is examined.

TL;DR: Staphylococcus caprae, whose major identification criteria are resumed, may have previously been misidentified as some similar CNS; this bacteria is probably part of the authors' normal flora but may be recognized as an opportunistic pathogen, responsible for both nosocomial and community acquired infections.

TL;DR: There is evidence of inadequate efficacy of preservatives present in ocular solutions, and unit-dose presentations may be preferable over multi- dose presentations for in hospital treatment.

TL;DR: These results confirm earlier in vitro studies demonstrating generation of active TGF-beta when endothelial cells are cocultured with smooth muscle cells or pericytes and shed new light on the mechanism of activation of latent T GF-beta possibly involved in vasculogenesis, angiogenesis, and other processes.

TL;DR: In this paper, the authors investigated the role of prostanoids and airway epithelium in the relaxation of guinea-pig airway smooth muscle and found that helicidine extract (0.001-1 mg/ml) induced a dose-dependent relaxation of trachea pre-contracted with histamine.

TL;DR: The impact of morphology on the diagnostic and prognostic approach to MM and MGUS, and on the planning and monitoring of appropriate therapy is emphasized.

TL;DR: In this paper, the authors show that the allogreffe de moelle induit dans environ 50 % des cases of myelome multiple en remission complete, c'est-a-dire la disparition des immunoglobulines anormales circulantes, des chaines legeres urinaires and des cellules myelomateuses medullaires.

TL;DR: The diagnosis of autoimmune liver disease can be made by assaying specific autoantibodies in the serum and a review is presented of these antibodies, the methods used to detect them, and the antigens identified to date.

TL;DR: A retrospective study of 44 cases of dengue fever diagnosed in nine french university hospitals between 1994 and 1997 finds that most patients were tourists and had been traveling for a few weeks, in French West Indies and French Guyana, South-East Asia, India, India or Polynesia, only two contracted the disease in Africa.

TL;DR: The beta S mutation responsible for sickle cell disease (SCD) was identified in 1949 and always consists in a T for A substitution at codon 6 of the beta-globin chain, resulting in deoxygenated HbS becoming polymerized, producing erythrocyte shape changes and vasoocclusion.

TL;DR: Improvement of the elastic properties of the aorta may be beneficial in altering the natural history of diseases, as shown in hypertensive patients compared to normotensive subjects and energy loss due to aortic wall viscosity is increased in the first group.

TL;DR: The present review discusses the incidence, risk factors, and diagnostic tools for infectious complications associated with long-term venous access devices, both for in-hospital care and at home.

TL;DR: Advances have been made in the minimization of BT-related complications (alloimmunization, viral infections, iron overload) through critical appraisal of the need for each BT, careful selection of the most appropriate blood product, and a change in BT technique resulting in a reduction in the number of blood donors.