Showing papers in "Seminars in Arthritis and Rheumatism in 1999"

TL;DR: SAPHO syndrome is a relevant and stable entity, with a good long-term prognosis, and NSAIDs and intraarticular injections (CS or osmic acid) most often alleviate rheumatic symptoms, but prednisone or methotrexate are sometimes necessary and appear globally helpful.

TL;DR: Minocycline has the potential to evoke a variety of clinical and serological autoimmune expressions, which should be suspected and investigated in young patients with autoimmune manifestations.

TL;DR: Cancer-associated rheumatic syndromes are discussed, aspects that may suggest the presence of a hidden cancer are called attention to, and the role of laboratory tests as clues of a possible neoplastic etiology of those syndrome are examined.

TL;DR: Although the value of ultrasonography in the evaluation of articular cartilage remains to be determined, this imaging method can be regarded as a useful bedside procedure for initial diagnostic screening of osteoarthritic femoral condylar cartilage.

TL;DR: The index of suspicion for rheumatic diseases in North American Indians and Eskimos should be high, and the severe disease and sometimes atypical presentations kept in mind, to help improve rheumatologic care.

TL;DR: The data presented in this review support the contention that NaPPS and CaPPS should be classified as SMOADs, however, additional long-term clinical studies employing methods of assessing joint structural changes will be needed to confirm this view.

TL;DR: OM is usually neglected when compared with other metabolic bone diseases and may present with a variety of clinical and radiographic manifestations mimicking other musculoskeletal disorders.

TL;DR: Long-term oral anticoagulation seems to be the best prophylactic treatment to prevent recurrences in patients with antiphospholipid syndrome and older age had an independent predictive value for rethrombosis.

TL;DR: In adults, HV and HSP as defined by these criteria, behave as two well-differentiated diseases, and HV has a milder course and lack of severe complications, andHSP a higher risk of gastrointestinal and renal complications.

TL;DR: The biochemical mechanisms underlying the therapeutic efficacy of low-dose methotrexate and leflunomide in the treatment of RA are quite different and the potentially complementary mechanisms of action of these two effective DMARDs should provide a rationale for their use in combination therapy for patients whose condition no longer responds to metotrexate alone.

TL;DR: Although a coincidental association between vaccination and the onset of SLE cannot be excluded, the temporal relationship with the development of symptoms makes it immunologically plausible that vaccination triggered systemic autoimmunity in these rare cases.

TL;DR: Evidence suggests an increased risk of specific cancers associated with the use of some treatments, but this may be outweighed by the potential benefit of therapy, especially in patients with severe disease.

TL;DR: In patients with documented HPV-B19 infection, the disease course was self-limiting with complete clinical remission and normalization of hematologic abnormalities within 18 months; one case, however, had persistent disease activity and repeated exacerbations.

TL;DR: The presence of aPL is associated with a higher prevalence of retinal abnormalities in SLE patients and the presence of anticardiolipin antibodies (aCL) (ELISA), lupus anticoagulant (LA) (coagulation tests), antinuclear antibodies (indirect immunofluorescence), anti-DNA (Farr's test), and anti-ENA antibodies (counterimmunoelectrophoresis).

TL;DR: Evidence indicates that men and women who are susceptible to premenopausal onset of RA can each be identified long before their clinical onsets of disease, and that productive research in primary prevention is an achievable objective.

TL;DR: HPV-B19 infection in a pediatric patient group may present with SLE-like symptomatology and positive serology suggestive of SLE, though the course of the disease is usually self-limited, though it may be prolonged in some for up to 120 weeks.

TL;DR: Clinical experience indicates that patients with refractory RA experience dramatic symptomatic relief, along with reduced fatigue and improved quality of life, thanks to etanercept.

TL;DR: A two-stage model of SS pathogenesis is proposed in which the initial process seems to be increased epithelial cell apoptosis leading to autoantibody production and subsequent salivary gland lymphocytic infiltration.

TL;DR: Oral pilocarpine is likely to benefit patients with SS by reducing the symptoms of xerostomia, even if the salivary gland secretion rate does not increase, and a recent multi-center study in SS patients suggests that oral pilocarine is effective and safe for long-term administration.

TL;DR: The high frequency of IF of the tibia and fibula seen in RA patients is probably due to the severe disease in patients treated by the Rheumatology Service and that such patients have a higher risk for osteoporosis and its complications.

TL;DR: RhG-CSF is an effective and generally well-tolerated treatment for neutropenia due to Felty's syndrome or systemic lupus erythematosus and appears to be rare if G- CSF is administered at the lowest dose effective at elevating the ANC above 1,000/microL.

TL;DR: The normal nail fold capillary network in children resembles that observed in adults with some differences, such as a lower number of loops per millimeter, a higher PVS score, and a higher frequency of atypical loops.

TL;DR: A young woman with pSS and severe CNS disease is described and the diagnosis is based on the clinical picture and the results of a brain magnetic resonance imaging scan, electroencephalography (EEG), and cerebrospinal fluid (CSF) analysis.

TL;DR: Two cases of chronic gouty arthritis masquerading as rheumatoid arthritis are described and clinical suspicion supplemented by characteristic laboratory, radiological and histologic findings help at reaching an accurate diagnosis.

TL;DR: A brief review of current thought on the role of T cells in the pathogenesis of rheumatoid arthritis and an overview of RA therapies directed against T cells are provided.

TL;DR: Infertility, the number of pregnancies, and pregnancy outcome are not strongly associated with the risk of developing RA in women of childbearing age and most other published studies find no association between nulliparity and RA.

TL;DR: An English translation of the first detailed description of lupus erythematosus along with a reproduction of thefirst color illustration of the disorder, as well as an interpretive analysis are provided.

TL;DR: This case illustrates the need to consider sarcoidosis, in addition to infections and neoplasms, in the differential diagnosis of peritoneal nodules and exudative ascites.

TL;DR: Three major forms of arthritis are common in rhesus macaques: osteoarthritis, spondyloarthropathy, and a category that might be referred to as apical plate excrescences (APE), which appears to present a natural model for characterization of genetic, immunologic, and environmental aspects of this phenomenon.