Showing papers in "The American Journal of Gastroenterology in 1993"
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TL;DR: Gastrointestinal and peritoneal tuberculosis remain common problems in impoverished areas of the world, but is relatively infrequent in the United States as discussed by the authors, and unless a high index of suspicion is maintained, the diagnosis can be missed or delayed resulting in increased morbidity and mortality.
653 citations
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TL;DR: The prevalence of colonic neoplasia in asymptomatic persons with negative fecal occult blood tests is substantial, particularly in elderly males, and a family history of a single first-degree relative diagnosed at age > or = 60 yr with colorectal cancer is not associated with an increased prevalence of Colonic adenomas.
345 citations
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TL;DR: The data suggest that controlled-release mesalamine capsules are a safe and effective monotherapy in doses of 2-4 g daily for treating mild to moderately active ulcerative colitis, as well as for inducing remission, regardless of prior oral steroid or sulfasalazine therapy or extent of disease.
278 citations
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TL;DR: Angiodysplasia is an important vascular lesion of the gut and a source of significant morbidity from bleeding, which has been purported to occur with higher frequency in patients with renal failure, von Willebrand's disease, aortic stenosis, cirrhosis, and pulmonary disease.
273 citations
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TL;DR: It is concluded that many patients with chronic hepatitis C eventually show progression of their disease after a long and symptomless course.
246 citations
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TL;DR: Intravenous CyA may prove to be a useful agent in the initial management of refractory Crohn's disease fistulas, although relapse as serum levels are lowered and infectious complications are limiting factors for long-term use as a single agent.
238 citations
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TL;DR: The symptoms subsided and the eosinophil counts returned to normal within 2 wk in seven patients and 1 month in one; of six patients being followed up for 2-10 yr, one had remission, four needed small maintenance dose of steroid, and one suffered from relapse with intestinal perforation.
233 citations
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TL;DR: It is concluded that erythromycin has a strong gastric prokinetic effect in both idiopathic and diabetic gastroparesis, and may represent a useful new therapeutic approach to this problem.
233 citations
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TL;DR: Clinithromycin is a promising antimicrobial in the eradication of H. pylori, but it is not sufficient to be used as monotherapy.
219 citations
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TL;DR: Esophageal resection is indicated in appropriately selected patients with Barrett's esophagus and high-grade dysplasia and perioperative complications can usually be managed conservatively.
215 citations
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TL;DR: The aims of this paper are to address concerns regarding the reliability and analysis of the EGG and the correlation between the E GG and gastric motility, and to review the potential clinical applications ofThe EGG.
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TL;DR: Oral sodium phosphate is a cost-effective colonoscopy preparation that is better tolerated and more effective than the polyethylene glycol-electrolyte lavage solution or castor oil and is projected to be $5000 per 100 patients at this center.
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TL;DR: The results show that the occurrence of refractory ascites has a prognostic value superior to those of other variables, and simple clinical and biochemical parameters, most of them components of the Child-Pugh score, are useful for a first screening of ascitic cirrhotic patients as candidates for liver transplantation.
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TL;DR: In this paper, a controlled study of the relationship among stress, psychological traits associated with chronic anxiety, acid reflux parameters, and perceptions of reflux symptoms was conducted using a 2 (high vs. low gastrointestinal susceptibility score) x 2 (stress vs. neutral tasks) x 3 (periods 1, 2, or 3) experimental design.
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TL;DR: It is suggested that total enteral nutrition is safe and nutritionally effective in severe attacks of ulcerative colitis and also cheaper and associated with fewer complications than parenteral nutrition.
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TL;DR: It is concluded that pneumatic dilation for esophageal achalasia performed in a graded fashion starting with Rigiflex 3.0-cm balloon dilator has a high success rate without complications in patients with a Chalasia.
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TL;DR: Minimal acid exposure occurred in the proximal esophagus in volunteers and patients with normal distal reflux and Patients with abnormal distal acid exposure had significantly greater proximal reflux.
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TL;DR: The results indicate that the gastric mucosa infected with HP is in a state of hyperproliferation, reflected in the reduction in number of polymorphonuclear and mononuclear cell infiltrates, and a reduction in the amount of superficial mucosa damage.
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TL;DR: Gas-forming pyogenic liver abscesses were common among the diabetics and Klebsiella pneumoniae was the major pathogen in both groups.
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TL;DR: High likelihood ratios and post-test probabilities for rebleeding were found for the number and severity of concurrent illnesses, but not for endoscopic stigmata, implying that the excess risk associated withStigmata is eliminated after effective endoscopic therapy, and clinical factors become the primary determinants of rebleeds.
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TL;DR: 6-MP was once again demonstrated to be effective in achieving major therapeutic goals in two of three patients with severe Crohn's disease, and the need for surgical resection and subsequent extension of the disease is often postponed or eliminated.
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TL;DR: The results of this study suggest that gastroesophageal reflux should be excluded in patients with noncardiac chest pain and nutcracker esophagus before initiation of smooth muscle relaxant therapy.
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TL;DR: The usefulness of the staining pattern of the Lugol test for the diagnosis of esophageal lesions such as squamous cell carcinoma and severe dysplasia is suggested, and the usefulness for precise delineation of the proximal resection line during surgery of esphageal carcinomas with unexpected wide extension is suggested.
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TL;DR: It is concluded that omeprazole-enhanced amoxicillin antibiosis is a simple and effective approach to the eradication of HP colonization.
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TL;DR: It will be important to control for influential patient factors in future studies of H. pylori treatment regimens, as successful eradication reduced the severity of both acute and chronic antral mucosal inflammation.
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TL;DR: The results suggest that sugar malabsorption may be implicated in the development of abdominal distress in at least a subset of patients with functional bowel disease.
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TL;DR: Patchy or absent inflammation of the rectum and sigmoid can be present in untreated children with UC at disease onset and these data must be considered when treatments or clinical research protocols are designed to include children with colitis.
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TL;DR: It appears that a new and powerful class of gastrointestinal prokinetic agents will evolve from erythromycin and its derivatives, and the role of motilin in the genesis of the fasting and fed patterns of gastrointestinal motility is emerging through the study of these motilIn agonists.
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TL;DR: Four of the nine patients with mucin-producing tumor of the pancreas exhibited obvious progression of pancreatic duct dilation in association with increased amounts of mucin in the dilated duct, whereas five did not show apparent progression of ductal changes.
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TL;DR: It is concluded that categorization of transplant referral patients with alcoholism and liver failure into predefined risk groups for recidivism and noncompliance accurately predicts pre- and post-transplant behavior.