Showing papers in "The American Journal of Medicine in 1977"

TL;DR: The major potent lipid risk factor was HDL cholesterol, which had an inverse association with the incidence of coronary heart disease in either men or women and these associations were equally significant even when other lipids and other standard risk factors for coronaryHeart disease were taken into consideration.

TL;DR: Single-enzyme phenotypes were found in erythrocytes, platelets and cultured blood macrophages indicating that these cells have a common stem cell which is the site of the abnormality in CML, and strong evidence that the disease has a clonal origin.

TL;DR: Most patients with cardiac sarcoidosis have little or no clinical evidence of dysfunction of an organ system other than the heart, and usually the course in patients with extensive cardiac sarCOidosis is not prolonged.

TL;DR: In this article, the relative role of depressed left ventricular ejection fraction and ventricular arrhythmias have been associated with a poor prognosis following acute myocardial infarction.

TL;DR: Daunomycin, like its anthracycline analog adriamycin, is a cardiotoxic antitumor antibiotic and dose-response curves constructed enable the clinician to judge the relative risk of developing cardiomyopathy at a given total dosage level and allows comparison of the human experience with the experimental animal model data.

TL;DR: Lung, breast, ovary and stomach were the most frequent primary sites, with carcinoma of the lung being the most common to involve the pleura; however, its incidence was relatively low.

TL;DR: The data support the thesis that the defect in these male pseudohermaphrodites is secondary to decreased steroid Δ 4 -5α-reductase activity and demonstrates an inherited disorder of steroid metabolism in which the basic enzyme deficiency resides in the target tissues.

TL;DR: Cardiac arrhythias during wakefulness and sleep in 15 patients with sleep-induced obstructive apnea, and the effect of atropine and tracheostomy on these arrhythmias were studied by continuous overnight Holter electrocardiographic, respiratory and electroencephalographic recordings.

TL;DR: It is suggested that angina pectoris and left ventricular dysfunction can occur with coronary artery aneurysm without coronary artery obstructions, and this process may involve other vascular territories.

TL;DR: The pattern of ocular disease, its relationship to systemic involvement, diagnostic methods and the response to therapy are discussed.

TL;DR: In view of the grave prognosis of established diffuse proliferative lupus nephritis, which probably evolves from a mesangial involvement common to all patients with SLE from its onset, early therapy may be the key to the management of lupuric syndrome.

TL;DR: The mortality in this series was low considering the severity of the underlying diseases and the immunosuppressed state of many of the patients, and mortality was further diminished by infectious disease consultation at the time the positive blood culture was reported.

TL;DR: The data indicate that relative intrinsic biologic potency and relative rates of disappearance from plasma are two of the most important factors in determining the relative glucocorticoid potency of orally administered glucOCorticoids.

TL;DR: The changed spectrum of purulent pericarditis likely reflects the therapeutic advances of the past 30 years including antibiotics, chemotherapy, hemodialysis and thoracic surgery.

TL;DR: The data from this study demonstrate that no clinical findings are specific for the diagnosis of pulmonary emboli, but the absence of isolated frequently occurring signs and symptoms should mitigate against the presence of pulmonaryemboli.

TL;DR: In this paper, the authors analyzed the prognostic factors of 56 patients with advanced diffuse histiocytic lymphoma who entered complete remission and showed that combining chemotherapy can dramatically improve the survival of those patients who enter complete remission.

TL;DR: It appears that survival time in patients treated with M-2 will be significantly longer than in the earlier group treated at this center with melphalan and prednisone alone.

TL;DR: Risk estimates have been developed for acute thyroiditis, hypothyroidism, and both benign and malignant thyroid nodules following exposure of the human thyroid to external and internal sources of ionizing radiation.

TL;DR: Patients with genitourinary tuberculosis exhibited features of local organ dysfunction rather than systemic symptoms of infection; fever, weight loss and anorexia were uncommon and tuberculosis salpingitis often requires laparotomy for diagnosis.

TL;DR: The process in four patients with chronic lymphocytic leukemia may be a distinctive chronic lymphoproliferative disorder originating in T lymphocytes with Fc receptors found in small numbers in the blood of normal persons.

TL;DR: With the shift of tuberculosis care to community hospitals, knowledge of the varied roentgenographic manifestations of pulmonary tuberculosis in the adult is of increasing importance for the practicing internist.

TL;DR: Two subtypes of patients identified as having persistent hypercalciuria during a period of low calcium intake were divided into two subtypes on the basis of their response to the administration of methylchlorothiazide and 25-hydroxyvitamin D 3.

TL;DR: The well recognized syndrome of "shrinking lungs" and high "sluggish" diaphragms with clear lung fields on radiography is probably due to dysfunction of thediaphragm rather than to primary intrapulmonary pathology.

TL;DR: Granulocyte transfusions are effective in the short-term control of infections in neutropenic patients with infection, and were most effective in patients with hypocellular marrows who failed to recover during the period of observation.

TL;DR: These laboratory results are reviewed in the light of the clinical spectrum of the renal injuries, and possible therapeutic implications of these new findings are briefly discussed.

TL;DR: The pathophysiology of hypoxemia in three patients with hepatic cirrhosis was investigated utilizing conventional cardiopulmonary tests and a special radionuclide technic for the detection of shunting through small dilated pulmonary vessels.

TL;DR: In this article, 12 cases of the primary empty sella syndrome were analyzed in regard to clinical findings, roentgenographic features, pituitary function and cerebrospinal fluid adenohypophysial hormone concentration.

TL;DR: Improved survival in both treatment groups was associated with the use of combinations of drugs that interacted synergistically in vitro, and a regimen which incorporates carbenicillin and either drug is equally effective, but empiric use of amikacin is indicated when there is a reasonable possibility of infection due to gentamicin-resistant organisms.

TL;DR: It is indicated that intravenous pyelography is dangerous in patients with juvenile onset diabetes who have a creatinine level of more than 5 mg/100 ml, and particularly at risk seem to be patients with early onset diabetes and those patients with severe renal failure.

TL;DR: The clinical, roentgenographic and histologic effects of the administration of bleomycin, methotrexate, busulfan and other cytotoxic agents on the lungs are discussed and it is suggested that these agents may also cause pulmonary malignancies.