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Showing papers in "The Journal of Pediatrics in 1970"


Journal ArticleDOI
TL;DR: A scoring system for gestational age, based on 10 neurologic and 11 “external” criteria, has been applied to 167 newborn infants and gives consistent results within the first 5 days and is equally reliable in the first 24 hours of life.

2,201 citations


Journal ArticleDOI
TL;DR: This constellation of findings, reported only once previously, probably represents an intrauterine alteration of cellular differentiation, affecting renal, gonadal, and other internal and external sexual structures.

372 citations


Journal ArticleDOI
TL;DR: A questionnaire has been developed for assessing temperamental characteristics of babies in the 4 to 8 month range and has been initially standardized on 101 babies in a single private practice, determining the presence of the characteristics of the difficult baby syndrome.

318 citations


Journal ArticleDOI
TL;DR: Predisposing factors significantly associated with meningitis were complications during labor and delivery, maternal peripartum infection, and chorioamnionitis.

198 citations


Journal ArticleDOI
TL;DR: Normative and atypical patterns of attachment are described; the nature of these patterns is determined by an interplay of maternal attitudes and specific infant behaviors.

188 citations


Journal ArticleDOI
TL;DR: A recent 3.5-fold increase in thrombosis of large vessels in autopsies is believed to be related to direct mechanical injury and alteration of flow in catheterized vessels.

181 citations



Journal ArticleDOI
TL;DR: From the data it appears that little, if any, of the retardation in weight and length that may be suffered in the fetal or neonatal period is made up during the 1st year of life if the infant's age is corrected to term.

171 citations


Journal ArticleDOI
TL;DR: Psychometric studies were performed on a group of 5-year-old children who had been jaundiced during neonatal life and a significant correlation was found between the presence or absence of brain damage and the saturation of the serum proteins with bilirubin during infancy.

164 citations


Journal ArticleDOI
TL;DR: The natural history and clinical findings of a probably X-linked recessive growth disorder, found in 7 affected males from 2 generations of the same family, have been described in this paper.

155 citations


Journal ArticleDOI
TL;DR: Incontrovertible evidence of intravascular coagulation seems necessary before heparin therapy can be recommended for the treatment of hemorrhage in patients with cyanotic congenital heart disease.


Journal ArticleDOI
TL;DR: Thirty-eight patients aged 2 to 18 years with hyperthyroidism were followed with hematologic studies while receiving propylthiouracil and ten had one or more episodes of leukopenia.

Journal ArticleDOI
TL;DR: In view of the poor response to medical therapy, a more aggressive surgical approach might be justified in selected patients with cystic fibrosis.

Journal ArticleDOI
TL;DR: Characteristics of family adaptation to the illnesses of 65 children with cystic fibrosis have been examined and certain phase-specific responses of the developing child to his disease which produce management crises are described.

Journal ArticleDOI
TL;DR: In this article, the effects of intravenously administered aminophylline were studied in 49 asthmatic children while they were symptomatic, and the safety of both methods of intravenous administration was documented by absence of adverse effects.

Journal ArticleDOI
TL;DR: Comparisons show that vital statistics derived from death certificates of infants dying during the neonatal period must be interpreted with great caution in certain of the major categories, as data so derived do not appear to reflect the actual frequency of these processes as causes of death.

Journal ArticleDOI
TL;DR: Fifteen cases from the files of the Armed Forces Institute of Pathology represent the largest series of renal cell carcinoma studied to date.

Journal ArticleDOI
TL;DR: Twenty-three patients had monosaccharide intolerance after an episode of gastroenteritis; some of the infants recovered the capacity to tolerate carbohydrates, and hypoglycemia complicated the clinical courses of 17 patients when they were fed carbohydrate-free diets.

Journal ArticleDOI
TL;DR: This study of patients aged 12 to 55 years clarifies the course of development of the 5p- syndrome and finds the catlike cry disappears and new features appear including strabismus, thin face, dental malocclusion, short metacarpals or metatarsals, scoliosis, small wings of the ilia, pes planus, and prematurely gray hair.

Journal ArticleDOI
TL;DR: The lung phospholipid content and composition were determined on 20 nonbreathing human fetuses and abortuses ranging in gestational age from 2 to 9 months and are compatible with the hypothesis that hyaline membrane disease is due to a prenatal deficiency of lung surfactant.

Journal ArticleDOI
TL;DR: A controlled clinical study compared the effectiveness of sponging with tepid water, ice water, and equal parts of 70 per cent isopropyl alcohol and water in addition to orally administered acetaminophen to reduce fever in children.

Journal ArticleDOI
TL;DR: Gas tensions, pH, and glucose concentrations of aortic blood were measured in 2 groups of normal newborn infants and it is postulated that the decreased Pa O 2, in the chilled infants was an effect of norepinephrine release on the pulmonary vascular bed.

Journal ArticleDOI
TL;DR: A new hereditary syndrome is described in 13 living members of 4 generations in a single kindred, characterized by malformations and hypoplasia of the hands and feet, and by varying degrees of duplication of the female genital tract.

Journal ArticleDOI
TL;DR: Although congenital cytomegalovirus infection in more than one sibling may be rare, the possibility of its occurrence should not be overlooked; infants born to the mother of a previously affected child should be subjected to long-term follow-up.

Journal ArticleDOI
TL;DR: These cells of the newly born infant showed normal metabolic response to phagocytosis in vitro and normal staphylocidal capacity in the presence of pooled normal human serum, indicating a functional maturity of these leukocytes as phagocytes.

Journal ArticleDOI
TL;DR: Observations suggest that Wolman's disease results from a deficiency of lysosomal esterolytic activity, leading to an accumulation of triglycerides and cholesteryl esters in swollen lysOSomes.

Journal ArticleDOI
TL;DR: In this paper, the coagulation factors were assayed in patients with cyanotic congenital heart disease, and the presence of cryofibrinogen and fibrinogenesis degradation products was found in association with polycythemia.

Journal ArticleDOI
TL;DR: Twenty-three children, aged 2 to 17 years, received 24 renal homotransplants from both live related donors and cadaver donors, and two children are surviving 1 to 32 months after transplantation.

Journal ArticleDOI
TL;DR: Juvenile diabetic patients had a strikingly increased incidence of thyroid and gastric antibodies, as compared with that of control subjects, and adult-onset diabetic patients, however, had essentially no difference in the incidence of antibodies.