Showing papers in "Toxicon in 1979"

TL;DR: Responses to ANTX-A on the isolated frog-rectus abdominus muscle were qualitatively similar to those obtained with acetylcholine, carbachol and decamethonium, with AN TX-A being the most potent.

TL;DR: Rattlesnake venom injected into live mice before they were swallowed by non-venomous snakes speeded the process of digestion, and proteolytic venom appears to be one of a group of characters that permit viperid snakes to swallow and digest large prey.

TL;DR: If validated in an extended range of venoms and antivenoms, ELISA screening of antivenom potency should be a useful standard procedure.

TL;DR: Venom of the fire ant ( Solenopsis invicta), long thought to contain only alkaloids, is shown to contain proteins, which undoubtedly accounts for the induction of anaphylactic reactions from stings.

TL;DR: The purity of the preparations was tested by sodium dodecyl sulphate gel electrophoresis, immunodiffusion and enzymatic methods for the presence of other known pseudomonal components.

TL;DR: Distinct biological properties were found for the esterases, E-I, EII and E-III showing kinin-releasing, fibrinolytic and clotting activity, respectively.

TL;DR: This institute's polyvalent snake antivenin was found to have measurable neutralizing effect on three of the venoms, but none whatever on the venom of the three medically most important scorpions, Androctonus, Buthotus and Odontobuthus .

TL;DR: The fibr inogen degradation products produced by β-fibrinogenase could polymerize with normal fibrin monomer, but prolonged the reaction time of thrombin with fibrInogen, a weak anticoagulant.

TL;DR: The results clearly show that the three animals studied are resistant to rattlesnake venom.

TL;DR: Comparison of metridiolysin with the SH-activated bacterial cytotoxins reveals that both are inhibitable by low concentrations of cholesterol and that both have biological effects that are broadly similar.

TL;DR: A lethal myotoxin, named mulgotoxin a, was isolated from the venom of the Australian king brown snake by chromatography on Biorex 70 and SP-Sephadex ion exchange resins, causing massive cell damage both in vivo and in vitro.

TL;DR: Chemical analysis showed that fraction c which contains the main coagulant activity in Dispholidus typus venom was a thermolabile glycoprotein and did not possess any of the caseinolytic or BAEE -hydrolyzing activities found in crude venom.

TL;DR: The potentiated maximal twitch observed in crotamine injected dogs is actually a brief tetanus, because the sustained contractions of the dog tibialis anterior muscle and the rat gastrocnemius are asynchronous tetanic contractions.

TL;DR: It is possible that antiserum to pure myotoxin could prevent the local myonecrosis induced by the pureMyotoxin, crude C. v. viridis venom and perhaps by other crotalid venoms.

TL;DR: Fractions 3, 4, 5, 6, 8 and 9 of the prep-disc electrophoretic separation of Loxosceles reclusa spider venom showed enzymic activity toward the hydrolysis of indoxyl-acetate and were therefore considered as hydrolytic enzyme components in the spider venom.

TL;DR: The employment of a device for the collection of scorpion venom, immediately after being released by natural stings, enabled a comparative study of venom obtained from individual Leiurus quinquestriatus scorpions and found a resemblance between the electrophoretic patterns of each of the three kinds of venom secretions obtained from the different scorpions.

TL;DR: Venom samples from the puff adder milked daily for a period of 5 days, largely abolished intra-individual venom variation with a more constant electrophoretic pattern for each individual as a result.

TL;DR: Vomitoxin was detected in 4 of 9 maize samples analysed and was quantitated by gas-liquid chromatography-mass spectrometry.

TL;DR: A quantitative in vitro hemolytic test has been developed based on observations that a component (or components) in venom from the brown recluse spider, Loxosceles reclusa, reacts with and alters human erythrocytes.

TL;DR: A survey for positive Litmlus amoebocyte lysate test in plasma from humans and common research animals and the role of platelet aggregation in rabbits made tolerant to endotoxin.

TL;DR: Injection of rats with a sublethal dose of Leiurus quinquestriatus venom induces an increase in the total lipid, cholesterol and phospholipid content of the liver and a decrease in free fatty acids, sphingomylin and lysolecithin in the serum.

TL;DR: Data suggest that the increase in vascular permeability to protein and red blood cells induced by the crude venom can, for the most part, be attributed to the peptide.

TL;DR: By means of Sephadex G-100 column chromatography, Vipera berus berus venom has been separated into ten fractions which have been tested for the following enzyme activities: phosphomonoesterase, phosphodiesterases, 5′-nucleotidase, protease, arginine ester hydrolase, hyaluronidase), ribonuclease and phospholipase.