Open AccessJournal Article
1989 Guidelines for the management of mild hypertension: Memorandum from a WHO/ISH meeting
Alberto Zanchetti,John Chalmers,P. Corvol,A. E. Doyle,D. Ganten,I. Gyarfas,L. Hansson,C. I. Johnston,S. Julius,H. Langford,A.F. Lever,Giuseppe Mancia,JL Reid,P. Sleight,T. Strasser,Judith A. Whitworth +15 more
TLDR
These guidelines are a revision of those published in 1986 and are based on the best available scientific evidence, and will be updated in the future to keep abreast of further developments in this field.Abstract:
The present guidelines were prepared by a subcommittee of the WHO/ISH (International Society of Hypertension) Mild Hypertension Liaison Committee, and wee finalized after discussion at the Fifth WHO/ISH Mild Hypertension Conference. They include the definition of mild hypertension, and describe blood pressure measurement, factors influencing the decision to begin treatment, methods of treatment, and follow-up. These guidelines are a revision of those published in 1986; they are based on the best available scientific evidence, and will be updated in the future to keep abreast of further developments in this field.read more
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Hypertension in the elderly is associated with white matter lesions and cognitive decline.
J. C. van Swieten,G. G. Geyskes,M. M. A. Derix,B. M. Peeck,L. M. P. Ramos,J.C. van Latum,J. van Gijn +6 more
TL;DR: It is suggested that long‐standing hypertension in some patients may cause not only strokes but also chronic end‐organ damage in the form of demyelination of the white matter, with cognitive decline.
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Elevated blood pressure and personality: a meta-analytic review.
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Doxazosin. An update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia.
TL;DR: Modelling-based calculations suggest that doxazosin significantly reduces the risk of developing coronary heart disease in patients with mild to moderate hypertension, although this remains to be confirmed in long term prospective studies.
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Guidelines on preventing cardiovascular disease in clinical practice.
TL;DR: This week's BMJ brings together a range of papers relevant to this paradigm shift in cardiovascular risk management, which has witnessed a remarkable change from recommendations based on relative risk to ones based on absolute risk—that is, incidence.
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Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: A comparative study of the efficacy and safety against amlodipine
Luigi Corea,Ondina Cardoni,Roberto Fogari,P. Innocenti,Carlo Porcellati,Michele Provvidenza,Susanne Meilenbrock,John L. Sullivan,Frédéric Bodin +8 more
TL;DR: To compare the antihypertensive efficacy of a new angiotensin II antagonist, valsartan, with a reference therapy, amlodipine, a new drug is introduced into the treatment of high-risk patients with high blood pressure.
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