Journal ArticleDOI
89-p: kir genotype distribution among symptomatic patients with and without helicobacter pylori infection: is there any role of the b haplotype?
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TLDR
Although there was no statistical significance in the difference between the KIR gene distributions among the two compared groups, a reduced distribution of A haplotype among the “H pylori negative” patients as compared to the ‘H. Pylori positive’ group may explain faster eradication of the organism.About:
This article is published in Human Immunology.The article was published on 2013-11-01. It has received 0 citations till now.read more
References
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The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma.
Santiago Coca,Javier Perez-Piqueras,David Martinez,Antonio Colmenarejo,Miguel A. Saez,Carmen Vallejo,Jose A. Martos,Manuel Moreno +7 more
TL;DR: Natural killer cells have a spontaneous cytotoxic capacity against tumor cells and represent a small proportion of human colon carcinoma‐infiltrating lymphocytes.
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Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection.
Janice M. Kelly,Phillip K. Darcy,Jessica L Markby,Dale I. Godfrey,Kazuyoshi Takeda,Hideo Yagita,Mark J. Smyth +6 more
TL;DR: CD27-CD70 interactions provide a key link between innate NK cell responses and adaptive T cell immunity in tumor cell lines that express CD70 and interact with CD27, which is constitutively expressed on NK cells.
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The Innate Immune Response Differs in Primary and Secondary Salmonella Infection
TL;DR: These studies provide a coherent view of innate immunity to oral Salmonella infection, reveal novel sources of IFN-γ, and demonstrate that immune status influences the nature of the innate response.
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HLA/KIR Restraint of HIV: Surviving the Fittest
TL;DR: Both genetic and functional data indicate that part of the HLA effect on HIV is due to interactions between KIR and HLA genes, also implicating natural killer cells in defense against viral infection and viral expansion prior to initiation of an adaptive response.
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Human Dendritic Cells Respond to Helicobacter pylori, Promoting NK Cell and Th1-Effector Responses In Vitro
Nadia Hafsi,Petra Voland,S. Schwendy,Roland Rad,Wolfgang Reindl,Markus Gerhard,Christian Prinz +6 more
TL;DR: H. pylori potently induced the maturation and activation of human monocyte-derived DC and thereby promote NK and Th1 effector responses, suggesting that membrane proteins may account for the specific adaptive immune response.
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