A
Arman Bashirova
Researcher at National Institutes of Health
Publications - 35
Citations - 2524
Arman Bashirova is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Human leukocyte antigen & Gene. The author has an hindex of 20, co-authored 31 publications receiving 2285 citations. Previous affiliations of Arman Bashirova include Ragon Institute of MGH, MIT and Harvard & Leidos.
Papers
More filters
Journal ArticleDOI
A Dendritic Cell–Specific Intercellular Adhesion Molecule 3–Grabbing Nonintegrin (Dc-Sign)–Related Protein Is Highly Expressed on Human Liver Sinusoidal Endothelial Cells and Promotes HIV-1 Infection
Arman Bashirova,Teunis B.H. Geijtenbeek,Gerard C.F. van Duijnhoven,Sandra J. van Vliet,Jeroen B.G. Eilering,Maureen P. Martin,Li-Li Wu,Thomas D. Martin,Nicola K. Viebig,Percy A. Knolle,Vineet N. KewalRamani,Yvette van Kooyk,Mary Carrington +12 more
TL;DR: It is proposed that L-SIGN may play an important role in the interaction between liver sinusoidal endothelium and trafficking lymphocytes, as well as function in the pathogenesis of HIV-1.
Journal ArticleDOI
The Killer Immunoglobulin-Like Receptor Gene Cluster: Tuning the Genome for Defense*
TL;DR: The polymorphism of the KIR locus parallels that of the MHC, facilitating the adaptation of the immune system to a dynamic, challenging environment.
Journal ArticleDOI
Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B.
Hathairat Thananchai,Geraldine M. Gillespie,Maureen P. Martin,Arman Bashirova,Nobuyo Yawata,Makoto Yawata,Philippa Easterbrook,Daniel W. McVicar,Katsumi Maenaka,Peter Parham,Mary Carrington,Tao Dong,Sarah Rowland-Jones +12 more
TL;DR: This study shows that HLA-A*2402 is a ligand for KIR3DL1 and demonstrates how the binding of KIR 3DL1 to Bw4+ ligands depends upon the bound peptide as well as HLA and KIR2DL1 polymorphism.
Journal ArticleDOI
AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis.
Xiaojiang Gao,Arman Bashirova,Astrid K. N. Iversen,J. P. Phair,James J. Goedert,Susan Buchbinder,Keith Hoots,David Vlahov,Marcus Altfeld,Stephen J. O'Brien,Mary Carrington +10 more
TL;DR: It is shown that three distinct HLA alleles known to alter the overall rate of AIDS progression act during distinct intervals after HIV-1 infection, which suggests alternative functional mechanisms in immune defense against this dynamic and chronic immunosuppressive disease.
Journal ArticleDOI
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load
Paul J. McLaren,Paul J. McLaren,Cédric Coulonges,Istvan Bartha,Istvan Bartha,Tobias L. Lenz,Aaron J. Deutsch,Aaron J. Deutsch,Aaron J. Deutsch,Arman Bashirova,Susan Buchbinder,Mary Carrington,Mary Carrington,Andrea Cossarizza,Judith Dalmau,Andrea De Luca,James J. Goedert,Deepti Gurdasani,Deepti Gurdasani,David W. Haas,Joshua T. Herbeck,Eric O. Johnson,Gregory D. Kirk,Olivier Lambotte,Ma Luo,Simon Mallal,Daniëlle van Manen,Javier Martinez-Picado,Javier Martinez-Picado,Laurence Meyer,José M. Miró,James I. Mullins,Niels Obel,Guido Poli,Guido Poli,Manjinder S. Sandhu,Manjinder S. Sandhu,Hanneke Schuitemaker,Patrick R. Shea,Ioannis Theodorou,Bruce D. Walker,Bruce D. Walker,Amy C. Weintrob,Cheryl A. Winkler,Steven M. Wolinsky,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,David Goldstein,Amalio Telenti,Paul I.W. de Bakker,Jean-François Zagury,Jacques Fellay,Jacques Fellay +53 more
TL;DR: Heritability analysis demonstrated that common human genetic variation—mostly in the HLA and CCR5 regions—explains 25% of the variability in viral load.