A Co-Evolution Theory of the Genetic Code
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The theory is proposed that the structure of the genetic code was determined by the sequence of evolutionary emergence of new amino acids within the primordial biochemical system.Abstract:
The theory is proposed that the structure of the genetic code was determined by the sequence of evolutionary emergence of new amino acids within the primordial biochemical system.read more
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References
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Journal ArticleDOI
The origin of the genetic code.
TL;DR: It is considered that originally only a few amino acids were coded, but that most of the possible codons were fairly soon brought into use and the code became frozen in its present form.
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On the evolution of the genetic code
TL;DR: In approaching the evolution of the genetic code the biologist will be forced to reexamine many of his fundamental prejudices, indeed, the meaning of Biology itself.
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Acyl Derivatives of Homoserine as Substrates for Homocysteine Synthesis in Neurospora crassa, Yeast, and Escherichia coli
Joyce L. Wiebers,H.R. Garner +1 more
TL;DR: End product feedback inhibition by l-methionine on the homocysteine synthetases, when the substrates used were acyl derivatives of homoserine, is described for the enzymes from Neurospora and yeast, but was not demonstrated with the enzyme from E. coli.
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Coding properties and nucleotide sequences of E. coli glutamine tRNAs.
William R. Folk,Moshe Yaniv +1 more
TL;DR: Advances in methods for tRNA purification and RNA sequence determination have aided in the elucidation of the sequences of approximately thirty tRNAs, providing insights into aspects of the recognition of mRNA codons by t RNAs, the specificity of protein-nucleic acid interactions and the mechanisms of post-transcriptional modification of RNAs.