Journal ArticleDOI
A comparative study of mass transfer in yeast for a batch pulsed baffled bioreactor and a stirred tank fermenter
TLDR
The kLa measurements and correlation with power density calculations for yeast re-suspension show that the kLa data in the pulsed baffled bioreactor are on average 75% higher than those obtained in the stirred tank (ST) fermenter.About:
This article is published in Chemical Engineering Science.The article was published on 1995-07-01. It has received 132 citations till now. The article focuses on the topics: Bioreactor.read more
Citations
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Journal ArticleDOI
Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization
Thomas McGlone,Naomi E. B. Briggs,Catriona A. Clark,Cameron J. Brown,Jan Sefcik,Alastair J. Florence +5 more
TL;DR: Oscillatory flow reactors (OFRs) offer a suitable platform to deliver consistent operating conditions under plug-flow operation while maintaining a controlled steady state as discussed by the authors, which is an attractive approach for the delivery of consistent particles with specified critical quality attributes (CQAs).
Journal ArticleDOI
Mixing Through Oscillations and Pulsations—A Guide to Achieving Process Enhancements in the Chemical and Process Industries
TL;DR: In this article, the authors review the concepts and key developments of mixing enhancement through pulsation and oscillation and focus on more recent research using oscillations in baffled tubes or columns, which generate discrete vortices as distinct from the more random type of flow produced by the well-established pulsed plate and reciprocating plate column devices.
Journal ArticleDOI
Design of a prototype miniature bioreactor for high throughput automated bioprocessing
TL;DR: A new miniature bioreactor with a diameter equal to that of a single well of a 24-well plate is described and its engineering performance as a fermenter assessed.
Journal ArticleDOI
Operation and Optimization of an Oscillatory Flow Continuous Reactor
TL;DR: A pilot-scale OFR was evaluated as a method for continuous production of sterols in an ester saponification reaction, and achieved the required product specification, in a residence time one-eighth that of a full-scale batch reactor.
Journal ArticleDOI
A Mixing-Based Design Methodology for Continuous Oscillatory Flow Reactors
P. Stonestreet,Adam Harvey +1 more
TL;DR: In this article, a shell-and-tube configuration for full-scale oscillatory flow Reactor (OFR) is presented, based on research done over the last four years to develop specific applications for OFRs.
References
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Image processing
TL;DR: Parts of image processing are discussed--specifically: the mathematical operations one is likely to encounter, and ways of implementing them by optics and on digital computers; image description; and image quality evaluation.
Book
Principles of Fermentation Technology
TL;DR: An introduction to fermentation processes is given in this article, where the authors discuss the isolation, preservation and improvement of industrially important micro-organisms and the development of inocula for industrial fermentations.
Related Papers (5)
Mixing and dispersion in a baffled tube for steady laminar and pulsatile flow
Malcolm R. Mackley,Xiongwei Ni +1 more