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A Convenient Method for the Preparation of Ketones by the Reaction of Grignard Reagents with Carboxylic Acid Derivatives

Masashi Araki, +3 more
- 01 Jul 1974 - 
- Vol. 47, Iss: 7, pp 1777-1780
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TLDR
In this article, it was found that ketones were prepared in excellent yields by the reaction of Grignard reagents with S-(2-pyridyl) thioates and their analogues or with 2-polycyclic esters.
Abstract: 
It was found that ketones were prepared in excellent yields by the reaction of Grignard reagents with S-(2-pyridyl) thioates and their analogues or with 2-pyridyl esters. The mechanism of this reac...

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Citations
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Journal ArticleDOI

Thiol Ester−Boronic Acid Coupling. A Mechanistically Unprecedented and General Ketone Synthesis

Lanny S. Liebeskind and, +1 more
- 26 Oct 2000 - 
Journal ArticleDOI

A New Ketone Synthesis by Palladium-Catalyzed Cross-Coupling Reactions of Esters with Organoboron Compounds

Hiroto Tatamidani, +2 more
- 10 Sep 2004 - 
TL;DR: The palladium-catalyzed coupling reaction of 2-pyridyl esters with organoboron compounds is described and the coordination of the nitrogen atom to Pd is a key step for efficient reaction.
Journal ArticleDOI

Levulinic acid in organic synthesis

Boris V Timokhin, +2 more
- 01 Jan 1999 - 
TL;DR: The wide synthetic potential of levulinic acid, particularly as a key compound in the synthesis of various heterocyclic systems, saturated and unsaturated ketones and diketones, difficultly accessible acids and other compounds is demonstrated in this article.
Journal ArticleDOI

Total synthesis of (+)-macbecin I

Raymond Baker, +1 more
- 01 Jan 1990 - 
TL;DR: The first enantiospecific synthesis of (+)-macbecin I has been performed in a convergent manner by coupling the epoxide (3) with a higher order cyanocuprate derived from the vinyl iodide (46) as mentioned in this paper.
Journal ArticleDOI

Metal-Catalyzed Synthesis and Use of Thioesters: Recent Developments

Vera Hirschbeck, +2 more
- 17 May 2018 - 
TL;DR: This work focuses on metal-catalyzed reactions for the synthesis of thioesters as well as their transformations, and various synthetically important compounds can by synthesized due to the multifaceted reactivity ofThioesters.
References
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Journal ArticleDOI

Reaction of S-(2-pyridyl) thioates with Grignard reagents. Convenient method for the preparation of ketones

Teruaki Mukaiyama, +2 more
- 01 Jul 1973 - 
Journal ArticleDOI

A Convenient Method for Hydrolysis of 1,3-Dithiane Derivatives Using Cupric Chloride

Koichi Narasaka, +2 more
- 01 Dec 1972 - 
Journal ArticleDOI

A Convenient Method for the Preparation of Thiolesters

Tadashi Endo, +2 more
- 01 Aug 1970 - 
Journal ArticleDOI

A Useful Method for Reductive Fission of Sulfides and Its Application to Carbon-Carbon Bond Formation

Teruaki Mukaiyama, +3 more
- 01 Aug 1971 - 
Journal ArticleDOI

Dihydro-1,3-oxazines. XVI. General synthesis of 2-alkylcyclopentenones and a method for adding CH2CO2Me to electrophilic olefins. Application to the synthesis of methyl jasmonate

A. I. Meyers, +1 more
- 01 Jan 1973 - 
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Reaction of S-(2-pyridyl) thioates with Grignard reagents. Convenient method for the preparation of ketones

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